Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254751 | 0.78 | MAPK1 (0.36) | TAAR1SLC6A2KCNN4MAPK1MAPT | |
| Ethane SCHEMBL8430515 | 0.76 | MAPK1 (0.35) | TAAR1SLC6A2MAPK1MAPTKMT2A | |
| SCHEMBL3318941 | 0.74 | ALDH1A1 (0.36) | TAAR1SLC6A2MAPK1MAPTKMT2A | |
| SCHEMBL7033571 | 0.74 | MAPK1 (0.33) | TAAR1SLC6A2MAPK1ALDH1A1ALOX15 | |
| SCHEMBL9805626 | 0.72 | KIF11 (0.47) | TAAR1SLC6A2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL3063901 | 0.70 | MAPK1 (0.36) | KCNN4MAPK1ALDH1A1ALOX15 | |
| SCHEMBL15147452 | 0.70 | RIPK1 (0.35) | TAAR1SLC6A2KCNN4MAPK1KMT2A | |
| SCHEMBL209178 | 0.69 | KCNN4 (0.58) | TAAR1SLC6A2KCNN4MAPK1MAPT | |
| SCHEMBL16766900 | 0.69 | TAAR1 (0.38) | TAAR1MAPK1KMT2AALDH1A1ALOX15 | |
| SCHEMBL2103073 | 0.69 | TSHR (0.33) | MAPK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101235113-B | Aryne resin containing polysilicone and preparation method thereof | UNIV EAST CHINA SCIENCE & TECH | 2010-04-14 | — | — | CN | disclosed |
| CN-101235113-A | Aryne resin containing polysilicone and preparation method thereof | UNIV EAST CHINA SCIENCE & TECH (CN) | 2008-08-06 | — | — | CN | disclosed |
| US-20070129331-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND PHARMACEUTICALS, INC. (US) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129331-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | PTGES2, PTGS2, SI | TAAR1 2888/4885SLC6A2 426/4885KCNN4 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.