Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SCD | O00767 | 3/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324193 | 0.78 | MAPK1 (0.46) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3350358 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3324070 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3350351 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3323897 | 0.74 | SMN1; SMN2 (0.60) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3100029 | 0.74 | SCD (0.53) | ALDH1A1HPGDSCDSCD5 | |
| SCHEMBL1238494 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3227629 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPK1HSD17B10SCDSCD5 | |
| SCHEMBL3324160 | 0.71 | SCD (0.67) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL14629954 | 0.70 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, ACSL6 | KDM4E 2490/4885ALDH1A1 2012/4885HPGD 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.