SCHEMBL3320871

SCHEMBL3320871

O=C(Cl)Oc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.40
CA2 P00918 2/20 0.39
CA12 O43570 5/20 0.37
CA1 P00915 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 3/20 0.37
MAPT P10636 3/20 0.36
CA4 P22748 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
GRM5 P41594 1/20 0.35
PTGES O14684 2/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
GAPDH P04406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12337780 0.85 ALOX15 (0.43) ALOX15TDP1ALDH1A1CA2CA12
SCHEMBL4474802 0.82 CA12 (0.51) TDP1ALDH1A1CA12CA9MAPT
SCHEMBL4204276 0.81 KMT2A (0.51) TDP1ALDH1A1CA2CA12CA9
SCHEMBL29426396 0.81 KMT2A (0.51) TDP1ALDH1A1CA2CA12CA9
SCHEMBL8968025 0.81 KMT2A (0.48) TDP1ALDH1A1CA2CA12CA9
SCHEMBL4598444 0.79 KMT2A (0.47) TDP1ALDH1A1CA2CA12CA1
SCHEMBL17481246 0.79 TYMS (0.46) ALOX15TDP1ALDH1A1CA2CA12
SCHEMBL31124167 0.79 KMT2A (0.47) TDP1ALDH1A1CA2CA12CA1
SCHEMBL31124079 0.79 KMT2A (0.47) TDP1ALDH1A1CA2CA12CA1
SCHEMBL3182253 0.79 KMT2A (0.46) ALOX15TDP1ALDH1A1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7727434-B2 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY (US) 2010-06-01 US disclosed
US-20070039874-A1 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY 2007-02-22 US disclosed