Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 7/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16741951 | 0.91 | CYP1A2 (0.47) | TDP1MAPTSMN1; SMN2LIN28ACYP3A4 | |
| SCHEMBL12087486 | 0.89 | HRH1 (0.43) | TDP1MAPTSMN1; SMN2LIN28ACYP3A4 | |
| SCHEMBL30007633 | 0.78 | MAPT (0.63) | TDP1MAPTSMN1; SMN2LIN28ACYP3A4 | |
| SCHEMBL12087476 | 0.77 | CYP3A4 (0.38) | TDP1MAPTSMN1; SMN2LIN28ACYP3A4 | |
| SCHEMBL20882979 | 0.77 | GAA (0.45) | TDP1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3461681 | 0.77 | CHRNB2 (0.45) | TDP1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL980114 | 0.75 | — | — | |
| SCHEMBL3461677 | 0.74 | CYP3A4 (0.42) | TDP1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16606318 | 0.74 | CYP1A2 (0.37) | TDP1MAPTSMN1; SMN2LIN28ACYP3A4 | |
| SCHEMBL214832 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160225471-A1 | FUNCTIONAL CONDUCTING POLYMERS FOR REDOX MEDIATED SEPARATIONS OF F-ELEMENTS | UNIV TEXAS (US) | 2016-08-04 | — | — | US | disclosed |
| US-8951695-B2 | Redox fuel cell with catholyte redox mediator | ACAL ENERGY LIMITED (GB) | 2015-02-10 | — | — | US | disclosed |
| US-8951695-B2 | Redox fuel cell with catholyte redox mediator | ACAL ENERGY LIMITED (GB) | 2015-02-10 | — | — | US | disclosed |
| US-20110091746-A1 | FUEL CELLS | ACAL ENERGY LIMITED (GB) | 2011-04-21 | — | — | US | disclosed |
| US-20110091746-A1 | FUEL CELLS | ACAL ENERGY LIMITED (GB) | 2011-04-21 | — | — | US | disclosed |
| JP-2010189339-A | N,N,N',N'-TETRAKIS(2-PYRAZINYLMETHYL)ETHYLENEDIAMINE DERIVATIVE, AND INTERMEDIATE THEREOF | KOBE UNIV | 2010-09-02 | — | — | JP | disclosed |