Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12339886 | 0.86 | POLB (0.44) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL14549272 | 0.81 | POLB (0.40) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL16429287 | 0.80 | POLB (0.56) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| Water SCHEMBL16429286 | 0.78 | POLB (0.54) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL28874324 | 0.77 | BACE1 (0.46) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL26002957 | 0.76 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL108713 | 0.75 | ALDH1A1 (0.77) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL28822417 | 0.75 | ALDH1A1 (0.77) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL29367250 | 0.75 | ALDH1A1 (0.77) | ALDH1A1GAAHSD17B10ALOX15MAPT | |
| SCHEMBL416690 | 0.75 | TDP1 (0.52) | ALDH1A1GAAHSD17B10ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121020-A1 | 3.3'-Diamino-5,5'-Diphenyl-4,4'-Biphenyldiol and Raw Material Thereof as Well as Polybenzoxazole | NIPPONKAYAKU KABUSHIKIKAISHA (JP) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121020-A1 | 3.3'-Diamino-5,5'-Diphenyl-4,4'-Biphenyldiol and Raw Material Thereof as Well as Polybenzoxazole | DDT, DDC, PBRM1 | ALDH1A1 347/4885GAA 2814/4885HSD17B10 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.