⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645669 | 0.64 | — | — | |
| SCHEMBL15296575 | 0.61 | IDO1 (0.39) | — | |
| SCHEMBL16417623 | 0.61 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL63709 | 0.60 | — | — | |
| SCHEMBL15830149 | 0.60 | — | — | |
| SCHEMBL13229296 | 0.57 | AXL (0.46) | — | |
| SCHEMBL399396 | 0.57 | NUDT1 (0.48) | — | |
| SCHEMBL31391522 | 0.57 | SRC (0.44) | — | |
| SCHEMBL9611700 | 0.57 | L3MBTL1 (0.47) | — | |
| SCHEMBL1155489 | 0.57 | SRC (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3498701-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2023-02-22 | — | — | EP | disclosed |
| US-11185531-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2021-11-30 | — | — | US | disclosed |
| US-10800743-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2020-10-13 | — | — | US | disclosed |
| EP-2970132-B1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2020-09-23 | — | — | EP | disclosed |
| US-20200289469-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2020-09-17 | — | — | US | disclosed |
| US-10632103-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190343826-A1 | TETRAHYDRO- AND DIHYDRO-ISOQUINOLINE PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2019-11-14 | — | — | US | disclosed |
| EP-2935247-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2019-08-28 | — | — | EP | disclosed |
| US-20190218194-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. | 2019-07-18 | — | — | US | disclosed |
| US-7875367-B2 | cyclopentaphenanthrene-based compound which is adapted for both dry and wet processes, and has excellent thermal stability and good charge transport and emission characteristics | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2011-01-25 | — | — | US | disclosed |
| US-7867629-B2 | Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-7867629-B2 | Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-7854999-B2 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2010-12-21 | — | — | US | disclosed |
| US-20100120763-A1 | IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES | WYETH (US) | 2010-05-13 | — | — | US | disclosed |
| US-20080100207-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2008-05-01 | — | — | US | disclosed |
| US-20080079356-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2008-04-03 | — | — | US | disclosed |
| US-20080079356-A1 | Organoelectroluminescent compound and organoelectroluminescent device employing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2008-04-03 | — | — | US | disclosed |
| US-20070287029-A1 | Aromatic Amine Compound and Organic Electroluminescent Device Using Same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| US-20070287029-A1 | Aromatic Amine Compound and Organic Electroluminescent Device Using Same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |