Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188045 | 1.00 | CA1 (0.46) | CA1CA2MAPTNPSR1ALDH1A1 | |
| SCHEMBL5143611 | 0.91 | LARS1 (0.43) | CA1CA2MAPTNPSR1ALDH1A1 | |
| SCHEMBL3198394 | 0.88 | CA1 (0.49) | CA1CA2MAPTALDH1A1KMT2A | |
| SCHEMBL3177957 | 0.82 | VCAM1 (0.58) | CA1CA2MAPTALDH1A1KDM4E | |
| SCHEMBL13335267 | 0.81 | CA2 (0.56) | CA1CA2ALDH1A1 | |
| SCHEMBL3198456 | 0.81 | CA2 (0.56) | CA1CA2ALDH1A1 | |
| SCHEMBL3177359 | 0.81 | CA2 (0.56) | CA1CA2ALDH1A1 | |
| SCHEMBL3178739 | 0.80 | SLC1A3 (0.48) | CA1CA2 | |
| SCHEMBL3194385 | 0.79 | CA1 (0.46) | CA1CA2ALDH1A1ALOX5APFEN1 | |
| SCHEMBL8349123 | 0.79 | MAPT (0.44) | CA1CA2MAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120725-A1 | Substituted Phenylsulfonamide Inhibitors of Beta Amyloid Production | WYETH LLC (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120725-A1 | Substituted Phenylsulfonamide Inhibitors of Beta Amyloid Production | APP, BACE1, PSEN1 | CA1 1302/4885CA2 3420/4885MAPT 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.