Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322002 | 0.84 | KMT2A (0.55) | HSD11B1ALDH1A1KMT2APOLBP2RX7 | |
| SCHEMBL13333014 | 0.80 | HSD11B1 (0.76) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 | |
| SCHEMBL9373354 | 0.76 | HDAC3 (0.51) | ALDH1A1KMT2APOLBKDM4EMAPT | |
| SCHEMBL12319896 | 0.73 | HSD11B1 (0.59) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 | |
| SCHEMBL13333063 | 0.71 | HSD11B1 (0.60) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 | |
| SCHEMBL3327946 | 0.71 | HSD11B1 (1.00) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 | |
| SCHEMBL13333013 | 0.71 | HSD11B1 (1.00) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 | |
| SCHEMBL3455848 | 0.70 | HPGD (1.00) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 | |
| SCHEMBL4002563 | 0.69 | HSD11B1 (0.50) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 | |
| SCHEMBL3949390 | 0.69 | HSD11B1 (0.63) | HSD11B1HPGDALDH1A1CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | HSD11B1 73/4885HPGD 3581/4885ALDH1A1 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.