⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758665 | 0.83 | TSHR (0.33) | — | |
| SCHEMBL331866 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL14695996 | 0.78 | — | — | |
| SCHEMBL4883022 | 0.76 | HPGD (0.30) | — | |
| SCHEMBL11039923 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL1582277 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL35421 | 0.70 | TDP1 (0.31) | — | |
| SCHEMBL14586215 | 0.70 | TSHR (0.36) | — | |
| SCHEMBL3478201 | 0.70 | — | — | |
| SCHEMBL159608 | 0.70 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11360241-B2 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2022-06-14 | — | — | US | claimed |
| US-20210149084-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2021-05-20 | — | — | US | claimed |
| US-10935696-B2 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-03-02 | — | — | US | claimed |
| US-20200233118-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2020-07-23 | — | — | US | claimed |
| US-10641926-B2 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-05-05 | — | — | US | claimed |
| EP-3053605-B1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2019-10-23 | — | — | EP | claimed |
| US-20190187332-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2019-06-20 | — | — | US | claimed |
| EP-2258412-B1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2019-05-01 | — | — | EP | claimed |
| US-10254443-B2 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2019-04-09 | — | — | US | claimed |
| US-20180203161-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2018-07-19 | — | — | US | claimed |
| US-20050255231-A1 | Silicone hydrogels having consistent concentrations of multi-functional polysiloxanes | JOHNSON & JOHNSON VISION CARE, INC. | 2005-11-17 | — | — | US | claimed |
| US-20050154080-A1 | Contact lenses for extended wear (without surface treatment, coating-free), formed by reacting polyvinylpyrrolidone and (2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy) methylsilane, then curing | JOHNSON & JOHNSON VISION CARE, INC. | 2005-07-14 | — | — | US | claimed |
| JP-2005518826-A | — | — | 2005-06-30 | — | — | JP | claimed |
| WO-2005005517-A2 | SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| EP-1425052-A2 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | Johnson & Johnson Vision Care, Inc. (US) | 2004-06-09 | — | — | EP | claimed |
| EP-1425053-A2 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | Johnson & Johnson Vision Care, Inc. (US) | 2004-06-09 | — | — | EP | claimed |
| US-20030162862-A1 | Contact lenses for extended wear (without surface treatment, coating-free), formed by reacting polyvinylpyrrolidone and (2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy) methylsilane, then curing | JOHNSON & JOHNSON VISION CARE, INC. | 2003-08-28 | — | — | US | claimed |
| US-20030125498-A1 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. | 2003-07-03 | — | — | US | claimed |
| WO-2003022322-A2 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-03-20 | — | — | WO | claimed |
| WO-2003022321-A2 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-03-20 | — | — | WO | claimed |