SCHEMBL758665

SCHEMBL758665

C=C(C)C(=O)OC(CC)C([SiH3])(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
THRB P10828 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883022 0.92 HPGD (0.30) TSHR
SCHEMBL3478201 0.85
SCHEMBL332528 0.83
SCHEMBL14695996 0.83
SCHEMBL584058 0.82 ALDH1A1 (0.38) TSHRTHRBALDH1A1
SCHEMBL3665950 0.81 THRB (0.36) TSHRTHRBALDH1A1
SCHEMBL14675514 0.79 TSHR (0.35) TSHRALDH1A1
SCHEMBL10789997 0.79 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL331866 0.78 TSHR (0.39) TSHRTHRBALDH1A1
SCHEMBL7025018 0.77 TSHR (0.36) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
US-7816464-B2 Polymer particle dispersion, cosmetic composition comprising it and cosmetic process using it L'OREAL, S.A. (FR) 2010-10-19 US claimed
EP-1560043-B1 Soft contact lenses JOHNSON & JOHNSON VISION CARE (US) 2008-06-18 EP claimed
EP-1560043-A1 Soft contact lenses Johnson & Johnson Vision Care, Inc. (US) 2005-08-03 EP claimed
US-6420441-B1 DISPERSING REMOVABLE CROSSLINKED POLYMER POROGENS IN A POLYSILOXANE, CURING, AND HEATING TO REMOVE POROGEN; LOW DIELECTRIC CONSTANT; HIGH POROSITY; INSULATION MATERIALS SHIPLEY COMPANY, L.L.C. 2002-07-16 US claimed
US-5998498-A SILICONE HYDROGEL JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1999-12-07 US claimed
EP-0940693-A2 Soft contact lenses Johnson & Johnson Vision Products, Inc. (US) 1999-09-08 EP claimed
EP-3699676-B1 METHOD FOR MANUFACTURING OPHTHALMIC LENS IN WHICH MEMBER IS EMBEDDED SEED CO LTD (JP) 2024-04-10 EP disclosed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP disclosed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US disclosed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP disclosed
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 EP disclosed
EP-1088848-A1 Porous materials Shipley Company LLC (US) 2001-04-04 EP disclosed
EP-0982361-A1 FLAME-RETARDANT RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2000-03-01 EP disclosed
US-5998498-A SILICONE HYDROGEL JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1999-12-07 US disclosed
EP-0940693-A2 Soft contact lenses Johnson & Johnson Vision Products, Inc. (US) 1999-09-08 EP disclosed
US-4987893-A Conformable bandage and coating material ROCHAL INDUSTRIES, INC. (US) 1991-01-29 US disclosed