Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35421 | 0.87 | TDP1 (0.31) | ALDH1A1 | |
| SCHEMBL332528 | 0.79 | — | — | |
| SCHEMBL8356574 | 0.79 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL9842186 | 0.78 | TSHR (0.47) | TSHRTHRBALDH1A1 | |
| SCHEMBL758665 | 0.78 | TSHR (0.33) | TSHRTHRBALDH1A1 | |
| SCHEMBL642805 | 0.78 | TSHR (0.44) | TSHRTHRBALDH1A1 | |
| SCHEMBL29011415 | 0.76 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL18171346 | 0.75 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL2189996 | 0.74 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL10980730 | 0.73 | TSHR (0.41) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| EP-4657145-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| EP-4657144-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| US-20250223392-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC (CH) | 2025-07-10 | — | — | US | claimed |
| US-12286501-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2025-04-29 | — | — | US | claimed |
| US-20240254269-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2024-08-01 | — | — | US | claimed |
| WO-2024065567-A1 | SILOXANE MONOMER, CONTACT LENS COMPOSITION AND CONTACT LENS | 晶硕光学股份有限公司 | 2024-04-04 | — | — | WO | claimed |
| WO-2024054562-A2 | SUPRAMOLECULAR HYBRID HYDROGELS FOR BURN AND WOUND DRESSINGS | TRUSTEES OF TUFTS COLLEGE (US) | 2024-03-14 | — | — | WO | claimed |
| US-11926689-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2024-03-12 | — | — | US | claimed |
| EP-1560043-B1 | Soft contact lenses | JOHNSON & JOHNSON VISION CARE (US) | 2008-06-18 | — | — | EP | claimed |
| US-20070229757-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. | 2007-10-04 | — | — | US | claimed |
| EP-1809344-A2 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | Johnson and Johnson Vision Care, Inc. (US) | 2007-07-25 | — | — | EP | claimed |
| US-7247692-B2 | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2007-07-24 | — | — | US | claimed |
| WO-2006039467-A2 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-04-13 | — | — | WO | claimed |
| US-20060074208-A1 | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE, INC. | 2006-04-06 | — | — | US | claimed |
| EP-1641863-A2 | SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES | Johnson & Johnson Vision Care, Inc. (US) | 2006-04-05 | — | — | EP | claimed |
| US-20050255231-A1 | Silicone hydrogels having consistent concentrations of multi-functional polysiloxanes | JOHNSON & JOHNSON VISION CARE, INC. | 2005-11-17 | — | — | US | claimed |
| EP-0940693-B1 | Soft contact lenses | JOHNSON & JOHNSON VISION CARE (US) | 2005-06-22 | — | — | EP | claimed |
| WO-2005005517-A2 | SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2005-01-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | CRYZ, STRA6, PHOSPHO1 | TSHR 2055/4885THRB 2097/4885ALDH1A1 1714/4885 |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | STRA6, CRYZ, SMCHD1 | TSHR 1985/4885THRB 2866/4885ALDH1A1 969/4885 |
| US-20050255231-A1 | Silicone hydrogels having consistent concentrations of multi-functional polysiloxanes | MMS19, FHIT, CAD | TSHR 4175/4885THRB 2958/4885ALDH1A1 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.