Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RAC1 | P63000 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029810 | 0.87 | MAPT (0.71) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL5605902 | 0.86 | MAPT (0.74) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL16085444 | 0.86 | MAPT (0.70) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL2024441 | 0.83 | MAPT (0.70) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL3327876 | 0.82 | MAPT (0.60) | MAPTALDH1A1GAAL3MBTL1NPC1 | |
| SCHEMBL4941162 | 0.80 | MAPT (0.66) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL27410358 | 0.79 | MAPT (0.61) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL3060394 | 0.79 | MAPT (0.50) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL4941158 | 0.78 | ALDH1A1 (0.74) | MAPTALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL13561177 | 0.78 | MAPT (0.74) | MAPTALDH1A1GAAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535371-B | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-116535371-A | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-110294749-B | (S) -1, 3-thiazole phenyl furan thiocarbamate compound and preparation method and application thereof | 华南农业大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-110183428-B | Furan thiocarbamate compound containing 1,2,3, 4-tetrazole and preparation method and application thereof | 华南农业大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-109265452-B | Substituted phenyl furan-2-mercaptothiazoline ketone compounds and preparation method and application thereof | 华南农业大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-107674070-B | Cyanoimine thiazolidine furan carboxamide compound and preparation method and application thereof | 华南农业大学 | 2020-12-29 | — | — | CN | disclosed |
| US-20100130483-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2010-05-27 | — | — | US | disclosed |
| US-7678788-B2 | Diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2010-03-16 | — | — | US | disclosed |
| EP-1599476-B1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH AS (DK) | 2009-10-14 | — | — | EP | disclosed |
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2006-07-06 | — | — | US | disclosed |
| EP-1599476-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076453-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130483-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | CHRNA6, CHRNA10, CHRNA2 | MAPT 1607/4885ALDH1A1 846/4885GAA 3247/4885 |
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | CHRNA6, CHRNA10, CHRNA2 | MAPT 1607/4885ALDH1A1 846/4885GAA 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.