Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326205 | 0.84 | CHRNA7 (0.53) | CHRNA7SLC9A1NPC1RAB9APDE4B | |
| SCHEMBL3326891 | 0.83 | PDE7A (0.48) | CHRNA7MEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL3329155 | 0.83 | PDE7A (0.48) | CHRNA7MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL3326252 | 0.77 | CHRNA7 (0.52) | CHRNA7NPC1RAB9APDE4BPDE4D | |
| SCHEMBL3326108 | 0.76 | CHRNA7 (0.51) | CHRNA7ALDH1A1PDE4B | |
| Chloromethane SCHEMBL3323025 | 0.76 | CHRNA7 (0.48) | CHRNA7NPC1RAB9APDE4BPDE4D | |
| SCHEMBL373086 | 0.74 | CHRNA7 (0.58) | CHRNA7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7061160 | 0.74 | ALDH1A1 (0.55) | CHRNA7MEN1ALDH1A1KMT2A | |
| SCHEMBL3330426 | 0.73 | KDM4E (0.50) | CHRNA7ALDH1A1NPC1RAB9APDE4B | |
| SCHEMBL2636644 | 0.73 | ALDH1A1 (0.68) | MEN1ALDH1A1HPGDKMT2ASLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130483-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2010-05-27 | — | — | US | claimed |
| EP-1599476-B1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH AS (DK) | 2009-10-14 | — | — | EP | claimed |
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2006-07-06 | — | — | US | claimed |
| US-20100130483-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2010-05-27 | — | — | US | disclosed |
| US-7678788-B2 | Diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2010-03-16 | — | — | US | disclosed |
| EP-1599476-B1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH AS (DK) | 2009-10-14 | — | — | EP | disclosed |
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130483-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | CHRNA6, CHRNA10, CHRNA2 | CHRNA7 6/4885MEN1 4000/4885ALDH1A1 846/4885 |
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | CHRNA6, CHRNA10, CHRNA2 | CHRNA7 6/4885MEN1 4000/4885ALDH1A1 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.