SCHEMBL332603

SCHEMBL332603

C=C(C)C(=O)OC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.41
TDP1 Q9NUW8 2/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19499560 0.93 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL19499564 0.91 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL395895 0.91 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL8546680 0.84 TSHR (0.33) TSHRALDH1A1THRB
SCHEMBL1046024 0.84 TSHR (0.44) TSHRALDH1A1THRBTDP1POLB
SCHEMBL9411488 0.84 TSHR (0.44) TSHRALDH1A1THRBTDP1POLB
SCHEMBL396761 0.84 TSHR (0.48) TSHRALDH1A1THRBTDP1POLB
SCHEMBL396532 0.82 TSHR (0.47) TSHRALDH1A1THRBTDP1POLB
SCHEMBL396535 0.82 TSHR (0.42) TSHRALDH1A1THRBTDP1POLB
SCHEMBL393244 0.82 TSHR (0.42) TSHRALDH1A1THRBTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 876 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600820-B2 Photocurable composition with high silicon content CANON KABUSHIKI KAISHA (JP) 2026-04-14 US claimed
US-20250368802-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY CANON KK (JP) 2025-12-04 US claimed
US-20240199816-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-20 US claimed
WO-2024123531-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-13 WO claimed
US-11897985-B2 Water extractable ophthalmic devices BAUSCH & LOMB INCORPORATED (US) 2024-02-13 US claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20220251269-A1 WATER EXTRACTABLE OPHTHALMIC DEVICES JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2022-08-11 US claimed
EP-1945231-B1 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL PARTNERS LLP (US) 2021-11-10 EP claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
EP-1809344-B2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2016-08-10 EP claimed
EP-0611367-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0611380-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0603268-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS. BAUSCH & LOMB (US) 1994-06-29 EP claimed
EP-0603270-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR MAKING THEM BAUSCH & LOMB INCORPORATED (US) 1994-06-29 EP claimed
WO-1993023774-A1 SURFACE WETTABLE SILICONE HYDROGELS BAUSCH & LOMB INCORPORATED (US) 1993-11-25 WO claimed
WO-1993009084-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993009154-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993009155-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993005085-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS BAUSCH & LOMB INCORPORATED (US) 1993-03-18 WO claimed
WO-1993005098-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS BAUSCH & LOMB INCORPORATED (US) 1993-03-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600820-B2 Photocurable composition with high silicon content BIRC2, ACP1, IRS1 TSHR 4173/4885ALDH1A1 3351/4885THRB 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.