SCHEMBL332618

SCHEMBL332618

O=C=NCc1ccc(Oc2ccc(CN=C=O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MIF P14174 4/20 0.46
ST14 Q9Y5Y6 1/20 0.39
LTA4H P09960 1/20 0.38
TRPA1 O75762 2/20 0.36
FFAR1 O14842 1/20 0.36
SRD5A2 P31213 2/20 0.35
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35
NAAA Q02083 1/20 0.35
CYP3A4 P08684 2/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20767073 0.92 LTA4H (0.50) MIFLTA4HTRPA1FFAR1SRD5A2
SCHEMBL21089 0.86 MIF (0.44) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL22471901 0.84 MIF (0.43) MIFTRPA1CYP3A4TSHRALDH1A1
Water SCHEMBL14972874 0.84 MIF (0.43) MIFTRPA1CYP3A4TSHRALDH1A1
Water SCHEMBL29040332 0.84 MIF (0.43) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL5372 0.83 MIF (0.67) MIFLTA4HCYP3A4TSHRALDH1A1
SCHEMBL22472348 0.80 MIF (0.41) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL20766472 0.80 NQO1 (0.52) MIFLTA4HTSHRALDH1A1HPGD
SCHEMBL18383715 0.80 MIF (0.41) MIFTRPA1CYP3A4TSHRALDH1A1
SCHEMBL31094964 0.79 MIF (0.40) MIFTRPA1CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 884 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP claimed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US claimed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US claimed
US-11149107-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2021-10-19 US claimed
US-11008418-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2021-05-18 US claimed
US-20200165375-A1 \"Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same\ PPG INDUSTRIES OHIO, INC. 2020-05-28 US claimed
US-10590230-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2020-03-17 US claimed
US-20200071451-A1 Aircraft Windows PPG INDUSTRIES, INC. 2020-03-05 US claimed
US-20180282470-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2018-10-04 US claimed
EP-2411433-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2018-06-20 EP claimed
WO-2009005835-A2 ACRYLATED URETHANES, PROCESSES FOR MAKING THE SAME AND CURABLE COMPOSITIONS INCLUDING THE SAME HENKEL CORPORATION (US) 2009-01-08 WO claimed
US-20090012202-A1 Acrylated Urethanes, Processes for Making the Same and Curable Compositions Including the Same HENKEL CORPORATION (US) 2009-01-08 US claimed
EP-2004720-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG Industries Ohio, Inc. (US) 2008-12-24 EP claimed
US-20070225468-A1 Polyurethanes prepared from polyester polyols and/or polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-09-27 US claimed
US-20070173601-A1 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-26 US claimed
US-20070167600-A1 Polyurethanes prepared from polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-19 US claimed
US-20070167601-A1 Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-19 US claimed
US-20070155942-A1 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-05 US claimed
US-20070149749-A1 Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-06-28 US claimed
WO-2007070627-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-06-21 WO claimed