SCHEMBL5372

SCHEMBL5372

COc1ccc(CN=C=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.67
MPI P34949 1/20 0.47
IDO1 P14902 3/20 0.47
APLNR P35414 1/20 0.46
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
CMA1 P23946 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
AGXT P21549 2/20 0.44
LTA4H P09960 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
PYCR1 P32322 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6895340 0.90 MIF (0.56) MIFMPIIDO1APLNRALDH1A1
SCHEMBL332618 0.83 MIF (0.46) MIFALDH1A1LTA4HCYP3A4TSHR
Phenylacetic Acid SCHEMBL7872638 0.83 KDM4E (0.52) MIFALDH1A1KDM4EMAPTLTA4H
SCHEMBL21089 0.82 MIF (0.44) MIFALDH1A1CYP3A4TSHR
SCHEMBL7876366 0.81 MIF (0.47) MIFKDM4EHTTLDHAACHE
SCHEMBL1845479 0.81 TAAR1 (0.50) MIFIDO1ALDH1A1CA12CA1
SCHEMBL20766472 0.81 NQO1 (0.52) MIFALDH1A1KDM4ECA12CA1
SCHEMBL22471901 0.80 MIF (0.43) MIFALDH1A1CYP3A4TSHR
Water SCHEMBL14972874 0.80 MIF (0.43) MIFALDH1A1CYP3A4TSHR
Water SCHEMBL29040332 0.80 MIF (0.43) MIFALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240154124-A1 NEGATIVE ELECTRODE PLATE AND LITHIUM-ION BATTERY COMPRISING SAME ZHUHAI COSMX BATTERY CO., LTD. (CN) 2024-05-09 US claimed
CN-109627429-B Preparation method of high molecular weight poly (gamma-butyrolactone) 青岛博远高分子材料研究院有限公司 2024-04-16 CN claimed
CN-108250415-B Poly (gamma-butyrolactone) -b-polylactic acid block copolymer and preparation method thereof 青岛科技大学 2020-09-04 CN claimed
WO-2020083180-A1 METHOD FOR PREPARING POLY(γ-BUTYROLACTONE) WITH HIGH MOLECULAR WEIGHT 青岛科技大学 2020-04-30 WO claimed
CN-110117359-A Poly- (gamma-butyrolacton) block copolymer of polyethers-b- and preparation method thereof 青岛科技大学 2019-08-13 CN claimed
CN-109627429-A A kind of preparation method of high-molecular-weight poly (gamma-butyrolacton) 青岛科技大学 2019-04-16 CN claimed
CN-106128947-B A kind of lithographic method of multi-layer graphene 山东赛帝格新材料有限责任公司 2019-01-29 CN claimed
CN-108250415-A A kind of poly- (gamma-butyrolacton)-b- polylactic-acid block copolymers and preparation method thereof 青岛科技大学 2018-07-06 CN claimed
CN-106128947-A A kind of lithographic method of multi-layer graphene 烟台市烯能新材料股份有限公司 2016-11-16 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-5714599-A Process for the preparation of ste specific 1'-spiro-nucleosides NOVARTIS CORPORATION (US) 1998-02-03 US claimed
US-20260144743-A1 COMPOUNDS TMEM16A LIMITED (GB) 2026-05-28 US disclosed
EP-4743459-A1 BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS D.E. Shaw Research, LLC (US) 2026-05-20 EP disclosed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
EP-4699655-A2 COMPOUNDS TMEM16A LIMITED (GB) 2026-02-25 EP disclosed
US-4285946-A ANOREXIGENIC AGENTS; TREATING DISTURBANCES OF THE METABOLISM OF LIPIDS HOECHST AKTIENGESELLSCHAFT (DE) 1981-08-25 US disclosed
US-4232951-A DISPLAY DEVICE FOR MEMORY OR TEMPERATURE FUNCTIONS ALLIED CHEMICAL CORPORATION (US) 1980-11-11 US disclosed
EP-0000656-A1 4\"-Ureido-oleandomycin derivatives, process for their preparation and their use in pharmaceutical compositions PFIZER INC. (US) 1979-02-07 EP disclosed
US-4085090-A Aromatic polymers containing a nitrogen-containing ring group, and process for preparation thereof TEIJIN LIMITED (JA) 1978-04-18 US disclosed
US-3931171-A FROM A 1,3-DIOXINONE-(4) AND AN ISOCYANATE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144743-A1 COMPOUNDS CACNA1E, TMEM109, CACNA1C MIF 4828/4885MPI 4505/4885IDO1 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.