SCHEMBL332622

SCHEMBL332622

C#CCN(C)CCCCC

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.44
MAOB P27338 4/20 0.42
S1PR2 O95136 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39
S1PR5 Q9H228 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
MAOA P21397 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
THPO P40225 1/20 0.39
RAB9A P51151 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4588691 0.98 DNM1 (0.48) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL8168522 0.98 DNM1 (0.48) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL4587698 0.98 DNM1 (0.48) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL3506846 0.98 DNM1 (0.48) DNM1MAOBS1PR2S1PR1S1PR3
Hydrochloric Acid SCHEMBL5618261 0.96 DNM1 (0.50) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL332286 0.93
Hydrochloric Acid SCHEMBL5617623 0.91 HPGD (0.41) MAOBNPC1ALDH1A1CYP1A2CYP3A4
Oxalic Acid SCHEMBL5618292 0.88 MAOB (0.47) MAOBS1PR2S1PR1S1PR3S1PR5
SCHEMBL7048097 0.82
Hydrochloric Acid SCHEMBL8665208 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2531181-A1 EXTENDED RELEASE FORMULATIONS OF RASAGILINE AND USES THEREOF Pharma Two B Ltd. (IL) 2012-12-12 EP claimed
US-20120301542-A1 EXTENDED RELEASE FORMULATIONS OF RASAGILINE AND USES THEREOF PHARMA TWO B LTD. (IL) 2012-11-29 US claimed
WO-2011095973-A1 EXTENDED RELEASE FORMULATIONS OF RASAGILINE AND USES THEREOF PHARMA TWO B LTD. (IL) 2011-08-11 WO claimed
US-20100267736-A1 METHODS AND COMPOSITIONS TO ENHANCE THE EFFICACY OF PHOSPHODIESTERASE INHIBITORS THOMAS THOMAS N 2010-10-21 US claimed
US-20100267735-A1 METHODS AND COMPOSITIONS TO ENHANCE THE EFFICACY OF PHOSPHODIESTERASE INHIBITORS THOMAS THOMAS N 2010-10-21 US claimed
EP-1686973-A4 COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIOVASCULAR DISORDERS AND DISEASES TECHNION RES & DEV FOUNDATION (IL) 2009-03-25 EP claimed
EP-1942881-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF RENAL FAILURE Technion Research and Development of Foundation, Ltd. (IL) 2008-07-16 EP claimed
US-20080090915-A1 METHOD FOR PREVENTING OR ATTENUATING ANTHRACYCLINE-INDUCED CARDIOTOXICITY TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2008-04-17 US claimed
WO-2007039909-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF RENAL FAILURE TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2007-04-12 WO claimed
US-20070082958-A1 Methods for treatment of renal failure TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2007-04-12 US claimed
US-20060287401-A1 Methods for treatment of cardiovascular disorders and diseases TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2006-12-21 US claimed
EP-1686973-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIOVASCULAR DISORDERS AND DISEASES TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (IL) 2006-08-09 EP claimed
US-20050171210-A1 Compositions and methods for treatment of cardiovascular disorders and diseases TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2005-08-04 US claimed
WO-2005051371-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIOVASCULAR DISORDERS AND DISEASES TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2005-06-09 WO claimed
US-20050009835-A1 Methods and compositions to enhance the efficacy of phosphodiesterase inhibitors THOMAS THOMAS NADACKAL (US) 2005-01-13 US claimed
EP-0573498-B1 ALIPHATIC PROPARGYLAMINES AS SELECTIVE MAO-B INHIBITORS AND AS NEUROPROTECTIVE AGENTS UNIV SASKATCHEWAN (CA) 1998-11-18 EP claimed
EP-4603095-A2 IMPROVED PHARMACEUTICAL FORMULATIONS Ferring B.V. (NL) 2025-08-20 EP disclosed
EP-3787596-B1 IMPROVED PHARMACEUTICAL FORMULATIONS FERRING BV (NL) 2025-06-25 EP disclosed
WO-1996037226-A2 COMBINATIONS FOR THE TREATMENT OF PARKINSONISM CONTAINING SELECTIVE NMDA ANTAGONISTS PFIZER INC. (US) 1996-11-28 WO disclosed
WO-1996026720-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOAMINE OXIDASE B INHIBITORS R.P. SCHERER LIMITED (GB) 1996-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009835-A1 Methods and compositions to enhance the efficacy of phosphodiesterase inhibitors PDE3A, PDE3B, PDE5A DNM1 2274/4885MAOB 13/4885S1PR2 1623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.