SCHEMBL4587698

SCHEMBL4587698

C#CCN(C)CCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.48
MAOB P27338 3/20 0.44
S1PR2 O95136 1/20 0.42
S1PR1 P21453 1/20 0.42
S1PR3 Q99500 1/20 0.42
S1PR5 Q9H228 1/20 0.42
GGPS1 O95749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3506846 1.00 DNM1 (0.48) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL8168522 1.00 DNM1 (0.48) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL4588691 1.00 DNM1 (0.48) DNM1MAOBS1PR2S1PR1S1PR3
Hydrochloric Acid SCHEMBL5618261 0.98 DNM1 (0.50) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL332622 0.98 DNM1 (0.44) DNM1MAOBS1PR2S1PR1S1PR3
SCHEMBL332286 0.91
Hydrochloric Acid SCHEMBL5617623 0.88 HPGD (0.41) MAOB
Oxalic Acid SCHEMBL5618292 0.86 MAOB (0.47) MAOBS1PR2S1PR1S1PR3S1PR5
SCHEMBL7048097 0.80
SCHEMBL14041818 0.80 MAOB (0.46) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4520765-A1 IONIZABLE CATIONIC LIPIDS INCORPORATING SILICON AldexChem Kft. (HU) 2025-03-12 EP claimed
EP-1942881-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF RENAL FAILURE Technion Research and Development of Foundation, Ltd. (IL) 2008-07-16 EP claimed
WO-2007039909-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF RENAL FAILURE TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2007-04-12 WO claimed
US-20070082958-A1 Methods for treatment of renal failure TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2007-04-12 US claimed
EP-1389216-B1 AVERMECTINS SUBSTITUTED IN THE 4\"-POSITION HAVING PESTICIDAL PROPERTIES MERIAL INC (US) 2017-02-22 EP disclosed
EP-0996612-B1 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS UNIV SASKATCHEWAN (CA) 2003-04-09 EP disclosed
US-6251950-B1 ADMINISTERING TO THE PATIENT AN ALIPHATIC-PROPARGYLAMINE OR SALT FOR THE TREATMENT OF ACUTE AND CHRONIC DISEASES IN WHICH CELL DEATH OCCURS BY APOPTOSIS OR FOR THE TREATMENT OF PREMATURE DEGENERATION OF CELLS IN MAMMALS UNIVERSITY OF SASKATCHEWAN (CA) 2001-06-26 US disclosed
EP-0996612-A2 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS University of Saskatchewan Technologies Inc. (CA) 2000-05-03 EP disclosed
WO-1999003817-A2 ALIPHATIC PROPARGYLAMINES AS CELLULAR RESCUE AGENTS UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) 1999-01-28 WO disclosed
US-5840979-A USEFUL IN THE TREATMENT AND PREVENTION OF DISEASES IN WHICH CELL DEATH OCCURS BY APOPTOSIS UNIVERSITY OF SASKATCHEWAN (CA) 1998-11-24 US disclosed