SCHEMBL3326331

SCHEMBL3326331

CC1(C)O[C@H]2[C@H](O)OC[C@H]2O1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.36
CA2 P00918 4/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
ACHE P22303 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
CA9 Q16790 3/20 0.33
CA12 O43570 2/20 0.31
CA4 P22748 2/20 0.31
CA5A P35218 2/20 0.31
CA7 P43166 2/20 0.31
CA14 Q9ULX7 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
CA6 P23280 1/20 0.31
CA13 Q8N1Q1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12389697 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL6932666 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL18026267 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL13298724 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL13318313 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL25381577 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL6931270 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL3207006 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL19519647 1.00 CA1 (0.36) CA1CA2MGAMGAASI
SCHEMBL12792418 1.00 CA1 (0.36) CA1CA2MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12083140-B2 Pharmaceutical composition for preventing and treating glaucoma, containing adenosine derivative FUTURE MEDICINE CO., LTD. (KR) 2024-09-10 US disclosed
EP-3603647-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING GLAUCOMA, CONTAINING ADENOSINE DERIVATIVE FUTURE MEDICINE CO LTD (KR) 2024-08-21 EP disclosed
CN-113616659-B Pharmaceutical composition containing adenosine derivative 未来制药有限公司 2024-08-09 CN disclosed
US-20220143029-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING NONALCOHOLIC STEATOHEPATITIS, HEPATIC FIBROSIS, AND LIVER CIRRHOSIS, COMPRISING ADENOSINE DERIVATIVES FUTURE MEDICINE CO., LTD. (KR) 2022-05-12 US disclosed
US-11266650-B2 Pharmaceutical composition for preventing and treating nonalcoholic steatohepatitis, hepatic fibrosis, and liver cirrhosis, comprising adenosine derivatives FUTURE MEDICINE CO., LTD. (KR) 2022-03-08 US disclosed
US-20210386771-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING GLAUCOMA, CONTAINING ADENOSINE DERIVATIVE FUTURE MEDICINE CO., LTD. (KR) 2021-12-16 US disclosed
US-11185556-B2 Pharmaceutical composition for preventing and treating glaucoma, containing adenosine derivative FUTURE MEDICINE CO., LTD. (KR) 2021-11-30 US disclosed
US-20200046711-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING NONALCOHOLIC STEATOHEPATITIS, HEPATIC FIBROSIS, AND LIVER CIRRHOSIS, COMPRISING ADENOSINE DERIVATIVES FUTURE MEDICINE CO., LTD. (KR) 2020-02-13 US disclosed
EP-3603647-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING GLAUCOMA, CONTAINING ADENOSINE DERIVATIVE Future Medicine Co., Ltd. (KR) 2020-02-05 EP disclosed
EP-3533452-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING NONALCOHOLIC STEATOHEPATITIS, HEPATIC FIBROSIS, AND LIVER CIRRHOSIS, COMPRISING ADENOSINE DERIVATIVES Future Medicine Co., Ltd. (KR) 2019-09-04 EP disclosed
US-9018371-B2 Adenosine derivatives, method for the synthesis thereof, and the pharmaceutical compositions for the prevention and treatment of the inflammatory diseases containing the same as an active ingredient FM THERAPEUTICS CO., LTD. (KR) 2015-04-28 US disclosed
EP-1551412-B1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DISEASES RELATED TO NEUROTROPHINES MINERVA PATENTS SA (LU) 2011-05-04 EP disclosed
US-20100137577-A1 ADENOSINE DERIVATIVES, METHOD FOR THE SYNTHESIS THEREOF, AND THE PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT FUTURE MEDICINE CO., LTD. (KR) 2010-06-03 US disclosed
US-7625892-B2 Pharmaceutical compositions for the treatment of diseases related to neurotrophines MIMETECH S.R.L. (IT) 2009-12-01 US disclosed
US-7625892-B2 Pharmaceutical compositions for the treatment of diseases related to neurotrophines MIMETECH S.R.L. (IT) 2009-12-01 US disclosed
EP-0832091-B1 C-4' MODIFIED ADENOSINE KINASE INHIBITORS GENSIA SICOR INC (US) 2004-01-14 EP disclosed
US-5763596-A PYROLO PYRIMIDINE AND PYRAZOLO PYRIMIDINE COMPOUMDS; TREATMENT OF CARDIOVASCULAR AND BRAIN DISORDERS, ANTIINFLAMMATORY AGENTS METABASIS THERAPEUTICS, INC. (US) 1998-06-09 US disclosed
US-5674998-A FOR TREATING CARDIOVASCULAR OR BRAIN DISORDERS, OR AS ANTIINFLAMMATORY AGENT GENSIA INC. (US) 1997-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185556-B2 Pharmaceutical composition for preventing and treating glaucoma, containing adenosine derivative ADORA1, ADORA2A, PDE3A CA1 3113/4885CA2 161/4885MGAM 2203/4885
US-12083140-B2 Pharmaceutical composition for preventing and treating glaucoma, containing adenosine derivative ADORA1, ADORA2A, ADORA3 CA1 3088/4885CA2 145/4885MGAM 2289/4885
US-20210386771-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING GLAUCOMA, CONTAINING ADENOSINE DERIVATIVE ADORA1, ADORA2A, ADORA3 CA1 3088/4885CA2 145/4885MGAM 2289/4885
US-20100137577-A1 ADENOSINE DERIVATIVES, METHOD FOR THE SYNTHESIS THEREOF, AND THE PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT ADORA3, ADORA2A, ADORA1 CA1 4342/4885CA2 3844/4885MGAM 3507/4885
US-20220143029-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING NONALCOHOLIC STEATOHEPATITIS, HEPATIC FIBROSIS, AND LIVER CIRRHOSIS, COMPRISING ADENOSINE DERIVATIVES SLC10A1, LIPC, ADORA1 CA1 4621/4885CA2 3277/4885MGAM 2857/4885
US-20200046711-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING NONALCOHOLIC STEATOHEPATITIS, HEPATIC FIBROSIS, AND LIVER CIRRHOSIS, COMPRISING ADENOSINE DERIVATIVES SLC10A1, ADORA1, LIPC CA1 4728/4885CA2 3425/4885MGAM 3258/4885
US-11266650-B2 Pharmaceutical composition for preventing and treating nonalcoholic steatohepatitis, hepatic fibrosis, and liver cirrhosis, comprising adenosine derivatives SLC10A1, ADORA1, LIPC CA1 4728/4885CA2 3425/4885MGAM 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.