SCHEMBL33268

SCHEMBL33268

CC1Cc2ccccc2N1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 5/20 0.55
BRD4 O60885 4/20 0.55
TSHR P16473 1/20 0.55
EP300 Q09472 1/20 0.55
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
RAB9A P51151 1/20 0.47
LMNA P02545 1/20 0.46
AR P10275 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1736809 1.00 CREBBP (0.55) CREBBPBRD4TSHREP300GAA
SCHEMBL29572486 1.00 CREBBP (0.55) CREBBPBRD4TSHREP300GAA
SCHEMBL12837999 1.00 CREBBP (0.55) CREBBPBRD4TSHREP300GAA
SCHEMBL1868013 1.00 CREBBP (0.55) CREBBPBRD4TSHREP300GAA
SCHEMBL10670441 0.81 CREBBP (0.57) CREBBPBRD4TSHREP300GAA
SCHEMBL4130897 0.78 MTNR1A (0.45) CREBBPBRD4TSHREP300GAA
SCHEMBL14946402 0.78 GAA (0.47) CREBBPBRD4TSHREP300GAA
SCHEMBL29641564 0.78 MTNR1A (0.45) CREBBPBRD4TSHREP300GAA
SCHEMBL19230496 0.78 BRD4 (0.46) CREBBPBRD4TSHREP300GAA
SCHEMBL424121 0.78 MTNR1A (0.45) CREBBPBRD4TSHREP300GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1068 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581069-A1 ANAEROBICALLY CURABLE COMPOSITIONS Henkel AG & Co. KGaA (DE) 2025-07-09 EP claimed
US-20250197690-A1 ANAEROBICALLY CURABLE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2025-06-19 US claimed
CN-222829645-U Integrated reaction tank for 2-methylindoline production 济南德瑞丰环保化工有限公司 2025-05-06 CN claimed
CN-119751330-A Synthesis method of indapamide intermediate-N-amino-2-methylindoline hydrochloride 天津力生制药股份有限公司 2025-04-04 CN claimed
CN-117069644-B Novel 2-methylindoline antitumor compound and preparation method and application thereof 北京中医药大学 2024-06-18 CN claimed
CN-117069676-B 6-Methoxybenzothiazole compound and preparation method and application thereof 北京中医药大学 2024-06-18 CN claimed
CN-116003448-B BODIPY near infrared fluorescent probe containing indoline polyethylenically recognized Abeta fiber and preparation method thereof 淮阴工学院 2024-06-11 CN claimed
WO-2024115863-A1 FUEL COMPOSITION COMPRISING A RENEWABLE BASE AND A NITROGEN-CONTAINING HETEROCYCLIC AROMATIC COMPOUND TOTALENERGIES ONETECH (FR) 2024-06-06 WO claimed
CN-118126048-A Preparation and application methods of cuporphyrin cyanine nano particles with switchable photodynamic and photothermal effects and chemical dynamic effects 北京化工大学 2024-06-04 CN claimed
CN-117980359-A Anaerobically curable compositions 汉高股份有限及两合公司 2024-05-03 CN claimed
EP-0495250-B1 Cationic 1,3,4 thiadiazole dyes BAYER AG (DE) 1996-01-31 EP claimed
US-5349100-A Chiral metallocene compounds and preparation thereof by creation of a chiral center by enantioselective hydride transfer EXXON CHEMICAL PATENTS INC. (US) 1994-09-20 US claimed
EP-0462017-B1 PROCESS FOR THE INDUSTRIAL PREPARATION OF 3-SULFAMOYL-4-CHLORO-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)BENZAMIDE FROM 2,3-DIHYDRO-2-METHYL-1H-INDOLE AND HYDROXYLAMINE-O-SULFONIC ACID ADIR ET COMPAGNIE (FR) 1993-07-28 EP claimed
WO-1992012112-A1 CHIRAL METALLOCENE COMPOUNDS AND PREPARATION THEREOF BY CREATION OF A CHIRAL CENTER BY ENANTIOSELECTIVE HYDRIDE TRANSFER EXXON CHEMICAL PATENTS INC. (US) 1992-07-23 WO claimed
EP-0495250-A1 Cationic 1,3,4 thiadiazole dyes BAYER AG (DE) 1992-07-22 EP claimed
US-5110946-A PREPARATION OF 4-CHLORO-3-SULPHAMOYL-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)-BENZAMIDE FROM 2,3-DIHYDRO-2-METHYL-1H-INDOLE AND HYDROXYLAMINE-O-SULPHONIC ACID ADIR ET COMPAGNIE (FR) 1992-05-05 US claimed
US-5101040-A PROCESS FOR THE INDUSTRIAL PREPARATION OF 4-CHLORO-3-SULFAMOYL-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)BENZAMIDE ADIR ET COMPAGNIE (FR) 1992-03-31 US claimed
EP-0462016-A1 Process for the industrial preparation of 4-chloro-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl) benzamide ADIR ET COMPAGNIE (FR) 1991-12-18 EP claimed
EP-0462017-A1 Process for the industrial preparation of 3-sulfamoyl-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide from 2,3-dihydro-2-methyl-1H-indole and hydroxylamine-O-sulfonic acid ADIR ET COMPAGNIE (FR) 1991-12-18 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed