Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324351 | 0.84 | ANPEP (0.45) | ALDH1A1KMT2A | |
| SCHEMBL16991744 | 0.81 | DPP4 (0.42) | AOC3KDM4EATMALOX5ADRA2A | |
| SCHEMBL16991770 | 0.81 | DPP4 (0.42) | AOC3KDM4EATMALOX5ADRA2A | |
| SCHEMBL14910544 | 0.81 | DPP4 (0.42) | AOC3KDM4EATMALOX5ADRA2A | |
| SCHEMBL14910547 | 0.81 | DPP4 (0.42) | AOC3KDM4EATMALOX5ADRA2A | |
| SCHEMBL28340791 | 0.78 | ATM (0.41) | AOC3KDM4EATMALOX5LMNA | |
| SCHEMBL14909537 | 0.77 | SLC6A2 (0.42) | AOC3KDM4EATMALOX5L3MBTL1 | |
| SCHEMBL1231239 | 0.77 | SLC6A2 (0.42) | AOC3KDM4EATMALOX5L3MBTL1 | |
| SCHEMBL9716115 | 0.77 | SLC6A2 (0.42) | AOC3KDM4EATMALOX5L3MBTL1 | |
| SCHEMBL17076397 | 0.76 | ATM (0.40) | AOC3KDM4EATMALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121052-A1 | Novel compounds for treating proliferative diseases | JAIN RAMA | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121052-A1 | Novel compounds for treating proliferative diseases | PDK1, PDK2, PDK3 | AOC3 4809/4885KDM4E 1195/4885ATM 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.