SCHEMBL3327149

SCHEMBL3327149

CC(=O)SC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL479385 0.79
SCHEMBL3748077 0.75
Potassium SCHEMBL31370905 0.75
SCHEMBL13481756 0.72 LMNA (0.39)
SCHEMBL7752121 0.72 LMNA (0.39)
SCHEMBL8341750 0.72
SCHEMBL7360426 0.72 LMNA (0.39)
SCHEMBL2367089 0.72
Ammonia Solution, Strong SCHEMBL9146129 0.70 CA1 (0.36)
Ammonia Solution, Strong SCHEMBL5962571 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3095467-B1 ANTIBODY-ENZYME CONJUGATE VENTANA MED SYST INC (US) 2020-05-06 EP disclosed
CN-108883125-A Controlled release and layered cyclodextrin inclusion complex vehicles 西泽普研究与发展有限责任公司 2018-11-23 CN disclosed
EP-2963011-B1 MOLECULAR CONJUGATE VENTANA MED SYST INC (US) 2018-05-09 EP disclosed
EP-3095467-A1 MOLECULAR CONJUGATE Ventana Medical Systems, Inc. (US) 2016-11-23 EP disclosed
US-20160195540-A1 Molecular Conjugate VENTANA MED SYST INC (US) 2016-07-07 US disclosed
US-9310373-B2 Molecular conjugate VENTANA MEDICAL SYSTEMS, INC. (US) 2016-04-12 US disclosed
EP-2963011-A1 MOLECULAR CONJUGATE Ventana Medical Systems, Inc. (US) 2016-01-06 EP disclosed
EP-1951316-B1 Molecular conjugate VENTANA MED SYST INC (US) 2015-08-19 EP disclosed
US-20140205995-A1 MOLECULAR CONJUGATE VENTANA MEDICAL SYSTEMS, INC. (US) 2014-07-24 US disclosed
US-20100136652-A1 Molecular Conjugate VENTANA MEDICAL SYSTEMS, INC. 2010-06-03 US disclosed
US-20070117153-A1 Molecular conjugate VENTANA MEDICAL SYSTEMS, INC. 2007-05-24 US disclosed
US-6307101-B1 AMIDES SUBSTITUTED WITH MERCAPTOALCOHOL OR MERCAPTOKETONE GROUPS CAMPBELL DAVID A (US) 2001-10-23 US disclosed
EP-0832100-B1 NOVEL INHIBITORS OF METALLOPROTEASES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AFFYMAX TECH NV (AN) 2000-04-05 EP disclosed
US-5929278-A Inhibitors of metalloproteases, pharmaceutical compositions comprising same and methods of their use AFFYMAX TECHNOLOGIES N.V. (GB) 1999-07-27 US disclosed
US-5840698-A ENZYME INHIBITORS OF MERCAPTOKETONES AND MERCAPTOALCOHOLS FOR CONTROLLING DISEASES OF TISSUE BREAKDOWN, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS OR ANTITUMOR AGENTS AFFYMAX TECHNOLOGIES N.V. (GB) 1998-11-24 US disclosed
US-5831004-A Inhibitors of metalloproteases, pharmaceutical compositions comprising same and methods of their use AFFYMAX TECHNOLOGIES N.V. (GB) 1998-11-03 US disclosed
EP-0832100-A4 NOVEL INHIBITORS OF METALLOPROTEASES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE AFFYMAX TECH NV (AN) 1998-09-02 EP disclosed
EP-0832100-A1 NOVEL INHIBITORS OF METALLOPROTEASES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE AFFYMAX TECHNOLOGIES N.V. (AN) 1998-04-01 EP disclosed
WO-1996040204-A1 NOVEL INHIBITORS OF COLLAGENASE-1 AND STROMELYSIN-I METALLOPROTEASES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE AFFYMAX TECHNOLOGIES, N.V. (AN) 1996-12-19 WO disclosed
WO-1996040738-A1 NOVEL INHIBITORS OF METALLOPROTEASES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE AFFYMAX TECHNOLOGIES, N.V. (AN) 1996-12-19 WO disclosed