SCHEMBL7752121

SCHEMBL7752121

C[C](SC(C)=O)SC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
TSHR P16473 1/20 0.36
THPO P40225 1/20 0.36
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
CA1 P00915 2/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL479385 0.82
SCHEMBL3748077 0.78
Potassium SCHEMBL31370905 0.78
SCHEMBL2367089 0.75
SCHEMBL7360426 0.75 LMNA (0.39) LMNATSHRTHPOFFAR3LCK
SCHEMBL8341750 0.75
SCHEMBL13481756 0.75 LMNA (0.39) LMNATSHRTHPOFFAR3LCK
SCHEMBL3327149 0.72
SCHEMBL3904356 0.69
SCHEMBL12576581 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242428-B1 NUCLEOSIDES AND NUCLEOSIDE DIMERS CONTAINING AN L-SUGAR IN AT LEAST ONE OF THE NUCLEOSIDES UNISEARCH LIMITED (AU) 2001-06-05 US disclosed
EP-1069903-A1 NOVEL NUCLEOSIDE ANALOGS AND USES IN TREATING DISEASE Lipitek International, Inc. (US) 2001-01-24 EP disclosed
WO-1999045935-A1 NOVEL NUCLEOSIDE ANALOGS AND USES IN TREATING DISEASE LIPITEK INTERNATIONAL, INC. (US) 1999-09-16 WO disclosed
US-5939402-A TREATING PLASMODIUM, VIRAL INFECTIONS OR PARASITES IN MAMMALS LIPITEK INTERNATIONAL, INC. (US) 1999-08-17 US disclosed
WO-1996033201-A1 ACYCLOVIR DERIVATIVES AS ANTIVIRAL AGENTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1996-10-24 WO disclosed