Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221013 | 0.87 | LMNA (0.46) | LMNASMN1; SMN2HPGD | |
| SCHEMBL8752120 | 0.85 | LMNA (0.38) | LMNASMN1; SMN2HPGDRECQLCA2 | |
| SCHEMBL8583659 | 0.82 | LMNA (0.42) | LMNASMN1; SMN2 | |
| SCHEMBL7775837 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2RECQL | |
| SCHEMBL8752124 | 0.77 | LMNA (0.39) | LMNASMN1; SMN2HPGD | |
| SCHEMBL371082 | 0.76 | LMNA (0.46) | LMNASMN1; SMN2HPGD | |
| SCHEMBL9076702 | 0.74 | LMNA (0.44) | LMNASMN1; SMN2HPGD | |
| SCHEMBL8726308 | 0.74 | LMNA (0.41) | LMNASMN1; SMN2HPGD | |
| SCHEMBL8933210 | 0.72 | LMNA (0.49) | LMNASMN1; SMN2HPGD | |
| SCHEMBL333577 | 0.72 | LMNA (0.45) | LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090081297-A1 | Use of surface tension reducing agents in aerosol formulations | MAP PHARMACEUTICALS, INC. | 2009-03-26 | — | — | US | claimed |
| EP-0756497-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING PHARMACEUTICALLY ACCEPTABLE CLAYS | NYCOMED IMAGING AS (NO) | 1997-02-05 | — | — | EP | claimed |
| EP-0746339-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES | NYCOMED IMAGING AS (NO) | 1996-12-11 | — | — | EP | claimed |
| US-5543133-A | PREPARING PREMIX OF CONTRAST AGENT AND SURFACTANT; REDUCTION OF PARTICLE SIZE | NANOSYSTEMS L.L.C. (US) | 1996-08-06 | — | — | US | claimed |
| WO-1995028969-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING PHARMACEUTICALLY ACCEPTABLE CLAYS | NYCOMED IMAGING AS (NO) | 1995-11-02 | — | — | WO | claimed |
| WO-1995022995-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES | NYCOMED IMAGING A/S (NO) | 1995-08-31 | — | — | WO | claimed |
| US-5429824-A | Use of tyloxapole as a nanoparticle stabilizer and dispersant | EASTMAN KODAK COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| US-5368837-A | X-ray contrast compositions containing an organic crystalline X-ray contrast agent and a cellulose derivative | STERLING WINTHROP INC. (US) | 1994-11-29 | — | — | US | claimed |
| US-5360604-A | FOR ORAL OR RETROGRADE EXAMINATION OF THE GASTROINTESTINAL TRACT | STERLING WINTHROP INC. (US) | 1994-11-01 | — | — | US | claimed |
| US-5318768-A | For gastrointestinal tract; film membrane, cation potentiator, particle surface modifier | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | claimed |
| US-5318767-A | X-ray contrast compositions useful in medical imaging | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | claimed |
| EP-0498482-A2 | X-ray contrast compositions useful in medical imaging | NanoSystems L.L.C. (US) | 1992-08-12 | — | — | EP | claimed |
| EP-2317982-B1 | METHODS OF PROCESSING COMPOSITIONS CONTAINING MICROPARTICLES | BAXTER INT (US) | 2017-10-11 | — | — | EP | disclosed |
| EP-2334393-B1 | METHODS OF PROCESSING MULTI-PHASIC DISPERSIONS | BAXTER INT (US) | 2015-12-02 | — | — | EP | disclosed |
| US-8986736-B2 | Method for delivering particulate drugs to tissues | BAXTER INTERNATIONAL INC. (US) | 2015-03-24 | — | — | US | disclosed |
| EP-2334396-B1 | METHODS OF PROCESSING MICROPARTICLES | BAXTER INT (US) | 2013-11-13 | — | — | EP | disclosed |
| US-5451393-A | X-ray contrast compositions useful in medical imaging | EASTMAN KODAK COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| US-5429824-A | Use of tyloxapole as a nanoparticle stabilizer and dispersant | EASTMAN KODAK COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5318767-A | X-ray contrast compositions useful in medical imaging | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0498482-A2 | X-ray contrast compositions useful in medical imaging | NanoSystems L.L.C. (US) | 1992-08-12 | — | — | EP | disclosed |