Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667841 | 0.82 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2ADRB2ADRB1ADRB3 | |
| SCHEMBL6361849 | 0.81 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL332859 | 0.81 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL9016334 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL8230945 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL7775837 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9852571 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL8814469 | 0.78 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL9413517 | 0.77 | LMNA (0.41) | LMNASMN1; SMN2ADRB2ADRB1ADRB3 | |
| SCHEMBL370072 | 0.77 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025182-A1 | PROCESS OF PREPARING X-RAY CONTRAST COMPOSITIONS CONTAINING NANOPARTICLES | NANOSYSTEMS L.L.C. (US) | 1996-08-22 | — | — | WO | disclosed |