Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3327232 | 1.00 | MAPT (0.51) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2690714 | 0.84 | PPARG (0.50) | MAPTKDM4ELMNAHTTKMT2A | |
| SCHEMBL29279528 | 0.81 | PRKDC (0.42) | MAPTSMN1; SMN2ALDH1A1LMNATNFRSF1A | |
| SCHEMBL27002115 | 0.81 | PRKDC (0.42) | MAPTSMN1; SMN2ALDH1A1LMNATNFRSF1A | |
| SCHEMBL2537055 | 0.81 | ERN1 (0.50) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7825925 | 0.79 | KMT2A (0.61) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7825926 | 0.79 | KMT2A (0.61) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8143973 | 0.78 | MAPT (0.43) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2541217 | 0.77 | PSEN1 (0.52) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL2389154 | 0.77 | PSEN1 (0.51) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100119424-A1 | CATALYST | ALMQUEST AB (SE) | 2010-05-13 | — | — | US | disclosed |