Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.57 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.57 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.51 |
| ▸ | TFEB | P19484 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825926 | 1.00 | KMT2A (0.61) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL28893878 | 0.86 | KDM4E (0.58) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL20424901 | 0.86 | KDM4E (0.58) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL2288436 | 0.85 | KMT2A (0.46) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL2690714 | 0.83 | PPARG (0.50) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL7824349 | 0.83 | PTGES (0.55) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL7824347 | 0.83 | PTGES (0.55) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL28418455 | 0.80 | LMNA (0.47) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL998236 | 0.80 | LMNA (0.64) | KMT2ALMNAKDM4EPKMMAPT | |
| SCHEMBL3327232 | 0.79 | MAPT (0.51) | KMT2ALMNAKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |