SCHEMBL332768

SCHEMBL332768

NC(=O)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL11543076 0.78
SCHEMBL18383800 0.78
SCHEMBL10791982 0.75 LDHA (0.43)
SCHEMBL10791983 0.75 LDHA (0.43)
Urea C 13 SCHEMBL12476878 0.72
Urea SCHEMBL7756359 0.72 LMNA (1.00)
Urea SCHEMBL20641124 0.72 LMNA (1.00)
Urea SCHEMBL411583 0.72
Urea SCHEMBL8434002 0.72 LMNA (1.00)
Urea SCHEMBL8560069 0.72 LMNA (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082260-A1 ICARITIN CARBAMATE PRODRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 沈阳药科大学 2025-04-24 WO claimed
CN-119841798-A Icaritin carbamate prodrug as well as preparation method and application thereof 沈阳药科大学 2025-04-18 CN claimed
CN-105002222-B Method for producing bioethanol using antibiotic alternatives 巴克曼实验室国际公司 2020-07-17 CN claimed
CN-101845002-B Tapentadol carbamate derivative and preparation method and application thereof UNIV SHENYANG PHARMACEUTICAL 2015-03-11 CN claimed
US-8263577-B2 Water-soluble iron carbohydrate derivative complexes, the preparation thereof, and medicaments comprising them VIFOR (INTERNATIONAL) AG (CH) 2012-09-11 US claimed
CN-102482244-A Covalent inhibition of bacterial quorum sensing NAT INST FOR BIOTECHNOLOGY IN THE NEGEV 2012-05-30 CN claimed
EP-2448930-A1 COVALENT INHIBITION OF BACTERIAL QUORUM SENSING The National Institute for Biotechnology in the Negev Ltd. (IL) 2012-05-09 EP claimed
WO-2011001419-A1 COVALENT INHIBITION OF BACTERIAL QUORUM SENSING NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV (IL) 2011-01-06 WO claimed
CN-101845002-A Tapentadol carbamate derivative and preparation method and application thereof UNIV SHENYANG PHARMACEUTICAL 2010-09-29 CN claimed
US-6730144-B2 MODIFIED LYSING ENZYME IMMOBILIZED ON SURFACE OF A HEPA FILTER NIKKI - UNIVERSAL CO., LTD. (JP) 2004-05-04 US claimed
US-20040050254-A1 AIR PURIFYING FILTER USING MODIFIED ENZYMES NIKKI-UNIVERSAL CO., LTD. (JP) 2004-03-18 US claimed
US-4958023-A 2-pyridinecarbothioamides, processes for preparation thereof and pharmaceutical compositions comprising the same AMERICAN HOME PRODUCTS CORPORATION (US) 1990-09-18 US claimed
EP-0088223-B1 MANUFACTURE OF ISOCYANATES AMERICAN CYANAMID COMPANY (US) 1985-04-17 EP claimed
EP-0088223-A1 Manufacture of isocyanates AMERICAN CYANAMID COMPANY (US) 1983-09-14 EP claimed
US-4379767-A Manufacture of isocyanates AMERICAN CYANAMID COMPANY (US) 1983-04-12 US claimed
US-4088665-A Process for the partial carbodiimidization of organic isocyanates BAYER AKTIENGESELLSCHAFT (DT) 1978-05-09 US claimed
US-12516191-B2 Isocyanurate-containing polyisocyanate composition with stable chromaticity, and preparation method thereof WANHUA CHEMICAL GROUP CO., LTD. (CN) 2026-01-06 US disclosed
US-20250236990-A1 Solid Support NOVARTIS AG (CH) 2025-07-24 US disclosed
US-3969388-A Manufacture of alkylisocyanates BASF AKTIENGESELLSCHAFT (DT) 1976-07-13 US disclosed
US-3969389-A Manufacture of aliphatic isocyanates BASF AKTIENGESELLSCHAFT (DT) 1976-07-13 US disclosed