Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3327731 | 1.00 | ESR1 (0.38) | ESR1TBXAS1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3329504 | 0.90 | MAPK8 (0.39) | ESR1SMN1; SMN2TSHRALDH1A1BRD4 | |
| SCHEMBL3328544 | 0.85 | ALDH1A1 (0.46) | TBXAS1SMN1; SMN2ALDH1A1GAAMEN1 | |
| SCHEMBL4750782 | 0.83 | TSHR (0.48) | SMN1; SMN2TSHRALDH1A1KDM4EGAA | |
| SCHEMBL3324327 | 0.80 | NPSR1 (0.39) | TBXAS1TSHRALDH1A1BRD4KDM4E | |
| SCHEMBL3324322 | 0.80 | NPSR1 (0.39) | TBXAS1TSHRALDH1A1BRD4KDM4E | |
| SCHEMBL3329506 | 0.77 | TSHR (0.47) | SMN1; SMN2TSHRALDH1A1KDM4EGAA | |
| SCHEMBL3329501 | 0.77 | TSHR (0.47) | SMN1; SMN2TSHRALDH1A1KDM4EGAA | |
| SCHEMBL3328122 | 0.76 | KDM4E (0.32) | SMN1; SMN2ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL3328126 | 0.76 | KDM4E (0.32) | SMN1; SMN2ALDH1A1KDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | DENOVAMED INC. (CA) | 2010-06-03 | — | — | US | claimed |
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | DENOVAMED INC. (CA) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | NAT1, NAPEPLD, NR1I2 | ESR1 1427/4885TBXAS1 1839/4885SMN1; SMN2 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.