Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471773 | 0.80 | KDM4E (0.48) | APPKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL6557649 | 0.78 | MAOB (0.57) | APPKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL6059021 | 0.78 | APP (0.50) | APPKDM4EALDH1A1CYP2A6DRD4 | |
| SCHEMBL18235025 | 0.76 | DRD4 (0.57) | APPKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL9080991 | 0.76 | APP (0.48) | APPKDM4EALDH1A1CYP2A6DRD4 | |
| SCHEMBL17445905 | 0.76 | ATM (0.60) | APPKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL7533336 | 0.76 | APP (0.58) | APPRXRARXRBCA1CA2 | |
| SCHEMBL2642306 | 0.75 | KDM4E (0.48) | APPKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL11563384 | 0.75 | ATM (0.50) | APPKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL13472002 | 0.75 | ATM (0.50) | APPKDM4EALDH1A1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120321533-A1 | CATALYST | ALMQVIST FREDRIK (SE) | 2012-12-20 | — | — | US | disclosed |
| US-20100119424-A1 | CATALYST | ALMQUEST AB (SE) | 2010-05-13 | — | — | US | disclosed |
| CN-101678330-A | Process for the production of palladium supported catalysts for catalyzing heck, suzuki-miyaura sonogashira coupling and buchwald-hartwig reactions | NORDIC CHEMQUEST AKTIEBOLAG | 2010-03-24 | — | — | CN | disclosed |
| EP-2152410-A2 | PROCESS FOR THE PRODUCTION OF PALLADIUM SUPPORTED CATALYSTS FOR CATALYZING HECK, SUZUKI-MIYAURA SONOGASHIRA COUPLING AND BUCHWALD-HARTWIG REACTIONS | Nordic chemquest Aktiebolag (SE) | 2010-02-17 | — | — | EP | disclosed |
| EP-1994983-A1 | Catalyst containing covalently bonded formate groups and Pd(0) and process for its obtention | Almquest AB (SE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2008138938-A2 | PROCESS FOR THE PRODUCTION OF PALLADIUM SUPPORTED CATALYSTS FOR CATALYZING HECK, SUZUKI-MIYAURA SONOGASHIRA COUPLING AND BUCHWALD-HARTWIG REACTIONS | NORDIC CHEMQUEST AB (SE) | 2008-11-20 | — | — | WO | disclosed |