Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 2/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 2/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375265 | 0.90 | PDPK1 (0.66) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL497199 | 0.90 | PDPK1 (0.66) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL29873925 | 0.90 | PDPK1 (0.66) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL8851 | 0.90 | PDPK1 (0.66) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| Isoguanine SCHEMBL887741 | 0.72 | PDPK1 (0.66) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| Isoguanine SCHEMBL29569323 | 0.72 | PDPK1 (0.66) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL2526552 | 0.71 | PDPK1 (0.44) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| 2,6-Diaminopurine SCHEMBL24053 | 0.71 | PDPK1 (1.00) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL533603 | 0.71 | PDPK1 (0.44) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| Ribose (Furanose) SCHEMBL4284369 | 0.71 | HIF1A (0.46) | PDPK1GDAPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137576-A1 | 5' O [(N ACYL)AMIDOPHOSPHATE] AND 5' O [(N ACYL)AMIDOTHIOPHOSPHATE] AND 5' O [(N ACYL)AMIDODITHIOPHOSPHATE] AND 5' O [(N ACYL)AMIDOSELENOPHOSPHATE] DERIVATIVES OF NUCLEOSIDES AND PROCESSES FOR THE MANUFACTURE THEREOF | CENTRUM BADAN MILEKULARNYCHI MAKROMOLEKULARNYCH, P (PL) | 2010-06-03 | — | — | US | claimed |
| EP-2097430-A1 | 5'-O-[(N-ACYL)AMIDOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDOTHIOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDODITHIOPHOSPHATE]- AND 5'-O-[N- ACYL)AMIDOSELENOPHOSPHATE-DERIVATIVES OF NUCLEOSIDES AND PROCESSES FOR THE MANUFACTURE THEREOF | Centrum Badan Molekularnych I Makromolekularnych Pan (PL) | 2009-09-09 | — | — | EP | claimed |
| WO-2008048128-A1 | 5'-O-[(N-ACYL)AMIDOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDOTHIOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDODITHIOPHOSPHATE]- AND 5'-O-[(N- ACYL)AMIDOSELENOPHOSPHATE]-DERIVATIVES OF NUCLEOSIDES AND PROCESSES FOR THE MANUFACTURE THEREOF | CENTRUM BADAN MOLEKULARNYCH I MAKROMOLEKULARNYCH, POLSKIEJ AKADEMII NAUK (PL) | 2008-04-24 | — | — | WO | claimed |