Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929934 | 0.83 | HDAC1 (0.54) | MTORPIK3CAHDAC1ESR2NR1H2 | |
| SCHEMBL13336894 | 0.78 | MAPK1 (0.59) | MTORPIK3CAABHD6NAMPTALDH1A1 | |
| SCHEMBL2335199 | 0.78 | ABHD6 (0.72) | MTORPIK3CAHDAC1ABHD6ESR2 | |
| SCHEMBL12177841 | 0.76 | HDAC1 (0.57) | MTORPIK3CAHDAC1ESR2NR1H2 | |
| SCHEMBL2809581 | 0.76 | ABHD6 (0.67) | MTORPIK3CAHDAC1ABHD6ESR2 | |
| SCHEMBL4229966 | 0.75 | USP2 (0.54) | MTORPIK3CAHDAC1ABHD6ESR2 | |
| SCHEMBL23253873 | 0.74 | HDAC1 (0.55) | MTORPIK3CAHDAC1ESR2NR1H2 | |
| SCHEMBL3328949 | 0.74 | HDAC1 (0.44) | MTORPIK3CAHDAC1ABHD6ESR2 | |
| SCHEMBL25669120 | 0.73 | PIK3CA (0.49) | MTORPIK3CAHDAC1ABHD6ESR2 | |
| SCHEMBL30368214 | 0.73 | PIK3CA (0.49) | MTORPIK3CAHDAC1ABHD6ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100119479-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119479-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | SARS1, VIP, MAVS | MTOR 4015/4885PIK3CA 3569/4885HDAC1 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.