Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324972 | 0.86 | KDM4E (0.39) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3329971 | 0.80 | TDP1 (0.36) | TDP1CYP3A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2469523 | 0.78 | NPC1 (0.44) | TDP1CYP3A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3330567 | 0.78 | KDM4A (0.48) | TDP1CYP3A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27529557 | 0.75 | TDP1 (0.36) | TDP1CYP3A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27503178 | 0.74 | TDP1 (0.37) | TDP1CYP3A4SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2470409 | 0.74 | HSP90AA1 (0.41) | TDP1HPGD | |
| SCHEMBL3331687 | 0.74 | TDP1 (0.35) | TDP1CYP3A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2465973 | 0.74 | KDM4E (0.47) | TDP1CYP3A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2466247 | 0.73 | DHODH (0.49) | TDP1SMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962523-B2 | Herbicide/safener combination | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| EP-1414814-B1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6784137-B2 | SUCH AS 5,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID-N-OXIDE FOR PREEMERGENCE APPLICATION | DOW AGROSCIENCES LLC | 2004-08-31 | — | — | US | disclosed |
| EP-1414814-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2003-06-19 | — | — | US | disclosed |
| WO-2003011853-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | TDP1 281/4885CYP3A4 244/4885SMN1; SMN2 520/4885 |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | AADAC, DDT, AADAT | TDP1 3914/4885CYP3A4 359/4885SMN1; SMN2 4252/4885 |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | TDP1 281/4885CYP3A4 244/4885SMN1; SMN2 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.