Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3329635 | 0.86 | TDP1 (0.36) | KDM4EPKMSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3328008 | 0.81 | KDM4E (0.39) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3330319 | 0.80 | KDM4E (0.41) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3324385 | 0.79 | KDM4E (0.45) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2468288 | 0.78 | KDM4E (0.38) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2470760 | 0.78 | HPGD (0.42) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2466172 | 0.77 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2466251 | 0.77 | KDM4E (0.44) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3839349 | 0.77 | KDM4E (0.44) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9938654 | 0.75 | NQO2 (0.40) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962523-B2 | Herbicide/safener combination | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| EP-1414814-B1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6784137-B2 | SUCH AS 5,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID-N-OXIDE FOR PREEMERGENCE APPLICATION | DOW AGROSCIENCES LLC | 2004-08-31 | — | — | US | disclosed |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | KDM4E 4579/4885PKM 3491/4885RCE1 3721/4885 |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | AADAC, DDT, AADAT | KDM4E 969/4885PKM 2868/4885RCE1 2703/4885 |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | KDM4E 4579/4885PKM 3491/4885RCE1 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.