Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.30 |
| ▸ | GABRE | P78334 | 2/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123205 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL16600318 | 0.81 | GABRP (0.50) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11693854 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNASLC15A2CA1 | |
| SCHEMBL19668472 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL14997347 | 0.74 | — | — | |
| SCHEMBL1224538 | 0.74 | — | — | |
| SCHEMBL8620882 | 0.74 | — | — | |
| SCHEMBL21310259 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNASLC15A2ACHE | |
| SCHEMBL16703406 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNASLC15A2 | |
| SCHEMBL13232365 | 0.73 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNASLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137232-A1 | COMPOSITION COMPRISING A DIURETIC AND A CARDIAC GLYCOSIDE FOR THE TREATMENT OF DNA VIRAL INFECTIONS OF THE EYE | HENDERSON MORLEY PLC (GB) | 2010-06-03 | — | — | US | disclosed |
| US-20070219142-A1 | Composition Comprising a Diuretic and/or Cardiac Glycosed for the Treatment of Dna Viral Infections of the Eye | HENDERSON MORLEY PLC (GB) | 2007-09-20 | — | — | US | disclosed |
| EP-1742638-A1 | COMPOSITION COMPRISING A DIURETIC AND/OR CARDIAC GLYCOSIDE FOR THE TREATMENT OF DNA VIRAL INFECTIONS OF THE EYE | Henderson Morley Plc (GB) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005102351-A1 | COMPOSITION COMPRISING A DIURETIC AND/OR CARDIAC GLYCOSIDE FOR THE TREATMENT OF DNA VIRAL INFECTIONS OF THE EYE | HENDERSON MORLEY PLC (GB) | 2005-11-03 | — | — | WO | disclosed |