Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.37 |
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.67 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.67 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL3772748 | 0.92 | GABRA1 (0.78) | GABRA1GABRB2PTPN2PTPN1TSHR | |
| Phosphoric Acid SCHEMBL7921309 | 0.92 | GABRA1 (0.78) | GABRA1GABRB2PTPN2PTPN1TSHR | |
| Phenol SCHEMBL5677167 | 0.90 | GABRA1 (0.82) | GABRA1GABRB2PTPN2PTPN1TSHR | |
| Hydrogen Peroxide SCHEMBL28937397 | 0.84 | GABRA1 (0.95) | GABRA1GABRB2TSHRLMNACA1 | |
| Benzene SCHEMBL1841233 | 0.84 | GABRA1 (0.95) | GABRA1GABRB2TSHRLMNACA1 | |
| SCHEMBL27923842 | 0.82 | GABRA1 (0.75) | GABRA1GABRB2PTPN2PTPN1TSHR | |
| SCHEMBL43297 | 0.82 | GABRA1 (1.00) | GABRA1GABRB2TSHRLMNACA1 | |
| SCHEMBL29531559 | 0.82 | GABRA1 (1.00) | GABRA1GABRB2TSHRLMNACA1 | |
| SCHEMBL15485453 | 0.82 | GABRA1 (1.00) | GABRA1GABRB2TSHRLMNACA1 | |
| Formaldehyde SCHEMBL27606839 | 0.80 | GABRA1 (0.86) | GABRA1GABRB2TSHRLMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851602-B2 | Epoxide and fluorinated epoxide stabilizers for fluoroolefins | THE CHEMOURS COMPANY FC, LLC (US) | 2023-12-26 | — | — | US | disclosed |
| US-20210380859-A1 | EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS | THE CHEMOURS COMPANY FC, LLC (US) | 2021-12-09 | — | — | US | disclosed |
| US-11130894-B2 | Epoxide and fluorinated epoxide stabilizers for fluoroolefins | THE CHEMOURS COMPANY FC, LLC (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200115605-A1 | EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS | THE CHEMOURS COMPANY FC, LLC (US) | 2020-04-16 | — | — | US | disclosed |
| EP-2420546-B2 | Terephthalate stabilizers for fluoroolefins | CHEMOURS CO FC LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-10550302-B2 | Epoxide and fluorinated epoxide stabilizers for fluoroolefins | THE CHEMOURS COMPANY FC, LLC (US) | 2020-02-04 | — | — | US | disclosed |
| EP-3470491-A1 | PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS | The Chemours Company FC, LLC (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2410032-B1 | Phosphorus-containing stabilizers for fluoroolefins | CHEMOURS CO FC LLC (US) | 2018-11-14 | — | — | EP | disclosed |
| US-20170362483-A1 | EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS | THE CHEMOURS COMPANY FC, LLC | 2017-12-21 | — | — | US | disclosed |
| US-9777204-B2 | Epoxide and fluorinated epoxide stabilizers for fluoroolefins | THE CHEMOURS COMPANY FC, LLC (US) | 2017-10-03 | — | — | US | disclosed |
| US-20090278097-A1 | flammable hydrofluorocarbon refrigerant (difluoroethane,1,1-); phosphate ester isopropoxylated triphenylphosphate fire reducing agent; and an additional fire hazard reducing agent comprising a carbonate salt (FeCO3 ) for reducing fire hazard in or in the vicinity of refrigerators and air conditioners | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-12 | — | — | US | disclosed |
| US-7560044-B2 | flammable hydrofluorocarbon refrigerant (difluoroethane,1,1-; phosphate ester isopropoxylated triphenylphosphate fire reducing agent; and an additional fire hazard reducing agent comprising a carbonate salt (FeCO3 ) for reducing fire hazard in or in the vicinity of refrigerators and air conditioners | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-14 | — | — | US | disclosed |
| EP-2069456-A1 | AMINE STABILIZERS FOR FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-2069454-A1 | EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-2057248-A2 | PHENOL STABILIZERS FOR FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008042066-A1 | AMINE STABILIZERS FOR FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008027594-A2 | PHENOL STABILIZERS FOR FLUOROOLEFINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2008027511-A1 | EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-06 | — | — | WO | disclosed |
| CN-1878849-A | Composition and method for reducing the fire hazard of flammable refrigerants | DU PONT (US) | 2006-12-13 | — | — | CN | disclosed |
| US-20050242323-A1 | flammable hydrofluorocarbon refrigerant (difluoroethane,1,1-; phosphate ester isopropoxylated triphenylphosphate fire reducing agent; and an additional fire hazard reducing agent comprising a carbonate salt (FeCO3 ) for reducing fire hazard in or in the vicinity of refrigerators and air conditioners | THE CHEMOURS COMPANY FC, LLC | 2005-11-03 | — | — | US | disclosed |