SCHEMBL3330873

SCHEMBL3330873

CCCC[CH]C(=O)CCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.52
CES2 O00748 4/20 0.50
CES1 P23141 4/20 0.50
PPARG P37231 4/20 0.48
PPARA Q07869 4/20 0.48
AKR1B1 P15121 1/20 0.48
TERT O14746 3/20 0.47
PTPN1 P18031 3/20 0.47
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.47
CYP2C19 P33261 2/20 0.47
BLM P54132 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FABP4 P15090 2/20 0.47
F7 P08709 2/20 0.47
F3 P13726 2/20 0.47
FAAH O00519 2/20 0.47
KMT2A Q03164 2/20 0.47
PPARD Q03181 2/20 0.47
GMNN O75496 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30675 0.98 CES2 (0.52) CES2CES1PPARGPPARATERT
SCHEMBL788432 0.98 CES2 (0.52) CES2CES1PPARGPPARATERT
SCHEMBL572485 0.98 CES2 (0.52) CES2CES1PPARGPPARATERT
SCHEMBL3512333 0.98 CES2 (0.52) CES2CES1PPARGPPARATERT
SCHEMBL7180871 0.98 CES2 (0.52) CES2CES1PPARGPPARATERT
SCHEMBL3212902 0.98 CES2 (0.52) CES2CES1PPARGPPARATERT
SCHEMBL1685059 0.93 PPARG (0.56) CES2CES1PPARGPPARATERT
SCHEMBL3397001 0.93 PPARG (0.56) CES2CES1PPARGPPARATERT
SCHEMBL10645729 0.93 PPARG (0.56) CES2CES1PPARGPPARATERT
SCHEMBL624501 0.93 PPARG (0.56) CES2CES1PPARGPPARATERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199612-B Porous adsorbent and preparation method and application thereof 荆楚理工学院 2024-06-21 CN claimed
CN-116199612-A Porous adsorbent and preparation method and application thereof 荆楚理工学院 2023-06-02 CN claimed
CN-103881069-B The manufacture of low-k bimaleimide resin 中国科学院上海有机化学研究所 2016-08-17 CN claimed
CN-103881069-A Manufacturing method of low-dielectric-constant bismaleimide resin SHANGHAI INST ORGANIC CHEM 2014-06-25 CN claimed
US-7524878-B2 Phenyl substituted carboxylic acids THE INSTITUTE FOR PHARMACEUTICALS DISCOVERY LLC (US) 2009-04-28 US claimed
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US claimed
CN-116199612-B Porous adsorbent and preparation method and application thereof 荆楚理工学院 2024-06-21 CN disclosed
CN-116199612-A Porous adsorbent and preparation method and application thereof 荆楚理工学院 2023-06-02 CN disclosed
CN-104311756-B Silicone containing bismaleimide resin and its preparation 中国科学院上海有机化学研究所 2018-07-10 CN disclosed
CN-103881069-B The manufacture of low-k bimaleimide resin 中国科学院上海有机化学研究所 2016-08-17 CN disclosed
CN-104311756-A Silicon-containing bismaleimide resin and preparation thereof SHANGHAI INST ORGANIC CHEM 2015-01-28 CN disclosed
CN-103881069-A Manufacturing method of low-dielectric-constant bismaleimide resin SHANGHAI INST ORGANIC CHEM 2014-06-25 CN disclosed
US-7741352-B2 KCNQ channel modulating compounds and their pharmaceutical use NEUROSEARCH A/S (DK) 2010-06-22 US disclosed
EP-1603858-A2 KCNQ CHANNEL MODULATING COMPOUNDS AND THEIR PHARMACEUTICAL USE NeuroSearch A/S (DK) 2005-12-14 EP disclosed
WO-2004080377-A2 KCNQ CHANNEL MODULATING COMPOUNDS AND THEIR PHARMACEUTICAL USE NEUROSEARCH A/S (DK) 2004-09-23 WO disclosed
US-20040014161-A1 pH-indicator based assay for selective enzymes THERMOGEN, INC. 2004-01-22 US disclosed
US-20020177180-A1 pH-indicator based assay for selective enzymes THERMOGEN, INC. 2002-11-28 US disclosed
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US disclosed
EP-1090139-A1 PH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES Thermogen, Inc. (US) 2001-04-11 EP disclosed
WO-1999067420-A1 pH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES THERMOGEN, INC. (US) 1999-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments MTTP, CETP, FABP1 TRPA1 1522/4885CES2 329/4885CES1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.