Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 8/20 | 0.52 |
| ▸ | PPARA | Q07869 | 8/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | TERT | O14746 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212902 | 1.00 | CES2 (0.52) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL30675 | 1.00 | CES2 (0.52) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL788432 | 1.00 | CES2 (0.52) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL572485 | 1.00 | CES2 (0.52) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL3512333 | 1.00 | CES2 (0.52) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL3330873 | 0.98 | TRPA1 (0.52) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL3397001 | 0.95 | PPARG (0.56) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL624501 | 0.95 | PPARG (0.56) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL1173224 | 0.95 | PPARG (0.56) | CES2CES1PPARGPPARAPPARD | |
| SCHEMBL9868698 | 0.95 | PPARG (0.56) | CES2CES1PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562958-B1 | Nucleotide sequences coding polypeptide for use in the treatment and prevention of infections | GENOME THERAPEUTICS CORPORATION | 2003-05-13 | — | — | US | disclosed |