SCHEMBL3330967

SCHEMBL3330967

c1ccc(SNc2ccc(Sc3ccc(NSc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.43
MAOB P27338 3/20 0.43
PTGIR P43119 1/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MGLL Q99685 1/20 0.42
ALDH1A1 P00352 2/20 0.41
SLC6A4 P31645 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.36
CHRNA7 P36544 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35
MAPK1 P28482 1/20 0.35
PTGS2 P35354 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL311562 0.85 HSD17B10 (0.50) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL19234396 0.80 HPGD (0.52) HPGDHSD17B10MAPTSMN1; SMN2MGLL
SCHEMBL8521589 0.80 MAOA (0.50) MAOAMAOBHPGDHSD17B10MAPT
SCHEMBL17948202 0.78 ALDH1A1 (0.60) MAOAMAOBPTGIRHPGDHSD17B10
SCHEMBL23277364 0.77 MAOA (0.62) MAOAMAOBHPGDHSD17B10MAPT
SCHEMBL3891151 0.77 MAOA (0.62) MAOAMAOBHPGDHSD17B10MAPT
SCHEMBL3891569 0.77 MAOA (0.62) MAOAMAOBHPGDHSD17B10MAPT
SCHEMBL795030 0.77 MAOA (0.62) MAOAMAOBHPGDHSD17B10MAPT
SCHEMBL11289053 0.76 HPGD (0.52) HPGDMAPTSMN1; SMN2ALDH1A1TSHR
SCHEMBL24986294 0.76 HSD17B10 (0.35) HPGDHSD17B10MAPTSMN1; SMN2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137490-A1 RESIN COMPOSITION, CURED PRODUCT AND OPTICAL PARTS TOKYO INSTITUTE OF TECHNOLOGY (JP) 2010-06-03 US disclosed
US-7714096-B2 Resin composition, cured product and optical parts TOKYO INSTITUTE OF TECHNOLOGY (JP) 2010-05-11 US disclosed
US-20080255284-A1 RESIN COMPOSITION, CURED PRODUCT AND OPTICAL PARTS TOKYO INSTITUTE OF TECHNOLOGY (JP) 2008-10-16 US disclosed
EP-1975192-A1 Resin composition, cured product and optical parts Tokyo Institute of Technology (JP) 2008-10-01 EP disclosed