Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332729 | 0.88 | ALOX5 (0.32) | ALOX5PIK3CD | |
| SCHEMBL332725 | 0.88 | ALOX5 (0.53) | ALOX5PIK3CDNAAAOTUD7BUSP30 | |
| SCHEMBL332345 | 0.88 | ALOX5 (0.42) | ALOX5NAAAOTUD7BUSP30 | |
| SCHEMBL3655644 | 0.85 | ALOX5 (0.42) | ALOX5NAAAOTUD7BUSP30 | |
| SCHEMBL12156883 | 0.81 | ALOX5 (0.38) | ALOX5NAAAOTUD7B | |
| SCHEMBL332739 | 0.81 | ALOX5 (0.38) | ALOX5NAAAOTUD7B | |
| SCHEMBL332822 | 0.80 | ALOX5 (0.63) | ALOX5PIK3CD | |
| SCHEMBL7802711 | 0.79 | ALOX5 (0.55) | ALOX5PIK3CD | |
| SCHEMBL8166281 | 0.79 | ALOX5 (0.55) | ALOX5PIK3CD | |
| SCHEMBL8172193 | 0.79 | ALOX5 (0.55) | ALOX5PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097733-B2 | Pyrazole derivatives as 5-LO-inhibitors | PFIZER INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20090227634-A1 | Pyrazole Derivatives as 5-LO-Inhibitors | PFIZER INC. | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227634-A1 | Pyrazole Derivatives as 5-LO-Inhibitors | ALOX5, ALOX15, CYP3A5 | ALOX5 1/4885PIK3CD 1305/4885NAAA 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.