SCHEMBL333300

SCHEMBL333300

O=C1CCCc2occc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
CYP2A6 P11509 1/20 0.42
PKM P14618 1/20 0.42
CYP2C19 P33261 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 3/20 0.39
POLB P06746 3/20 0.39
GAA P10253 1/20 0.39
CYP19A1 P11511 2/20 0.38
TBXAS1 P24557 2/20 0.38
KDM4E B2RXH2 2/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
PRKCI P41743 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3129135 0.96 HSD17B10 (0.39) MAPTMAOAMAOBCYP2A6PKM
SCHEMBL12180626 0.74 MAPT (0.39) MAPTPKMCYP2C19ALDH1A1HSD17B10
SCHEMBL13090140 0.74 MAPT (0.39) MAPTPKMCYP2C19ALDH1A1HSD17B10
SCHEMBL20721152 0.70 MAPT (0.37) MAPTPKMCYP2C19ALDH1A1HSD17B10
SCHEMBL18878451 0.69 MAPT (0.39) MAPTPKMCYP2C19ALDH1A1HSD17B10
SCHEMBL2588817 0.69 MAPT (0.52) MAPTPKMCYP2C19ALDH1A1HSD17B10
SCHEMBL2588819 0.69 MAPT (0.52) MAPTPKMCYP2C19ALDH1A1HSD17B10
SCHEMBL9865613 0.68 ALDH1A1 (0.34) MAOAMAOBCYP2A6ALDH1A1PRKCI
SCHEMBL10736420 0.68 HTR2C (0.33) HSD17B10POLBGAAKDM4ETSHR
SCHEMBL3227687 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507201-B Water wampee seed element derivative and preparation method and application thereof 常州大学 2023-06-27 CN claimed
CN-110128382-B Preparation method and application of phellinus igniarius seed extract 常州大学 2022-11-01 CN claimed
CN-114507201-A Cortinarius fruit seed derivative and preparation method and application thereof 常州大学 2022-05-17 CN claimed
EP-3470491-A1 PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS The Chemours Company FC, LLC (US) 2019-04-17 EP claimed
EP-2410032-B1 Phosphorus-containing stabilizers for fluoroolefins CHEMOURS CO FC LLC (US) 2018-11-14 EP claimed
US-20170362483-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS THE CHEMOURS COMPANY FC, LLC 2017-12-21 US claimed
EP-2420546-B1 Terephthalate stabilizers for fluoroolefins CHEMOURS CO FC LLC (US) 2017-04-26 EP claimed
EP-2057247-B1 ASCORBIC ACID STABILIZERS FOR FLUOROOLEFINS DU PONT (US) 2016-04-13 EP claimed
US-20150337192-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2015-11-26 US claimed
US-8668791-B2 Ascorbic acid, terephthalate and nitromethane stabilizers for fluoroolefins E I DU PONT DE NEMOURS AND COMPANY (US) 2014-03-11 US claimed
EP-0780118-A1 Compositions for dyeing keratinous fibers containing N-substituted 4-hydroxy indoline derivatives, and certain of these derivatives L'OREAL (FR) 1997-06-25 EP claimed
WO-1997003049-A1 N-SUBSTITUTED 4-HYDROXYINDOLE DERIVATIVES AND KERATIN FIBRE DYEING COMPOSITIONS CONTAINING SAME L'OREAL (FR) 1997-01-30 WO claimed
EP-0754681-A1 N-substituted 4-hydroxy-indole derivatives and compositions for dyeing keratinous fibers containing them L'OREAL (FR) 1997-01-22 EP claimed
EP-0101003-B2 PROCESS FOR PREPARING 4-OXO-4,5,6,7-TETRAHYDROBENZOFURAN DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-01-08 EP claimed
EP-0101004-B2 PROCESS FOR PREPARING 4-OXO-4, 5, 6, 7-TETRAHYDROINDOLE DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-16 EP claimed
EP-0101004-B1 PROCESS FOR PREPARING 4-OXO-4, 5, 6, 7-TETRAHYDROINDOLE DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-01-21 EP claimed
EP-0101003-B1 PROCESS FOR PREPARING 4-OXO-4,5,6,7-TETRAHYDROBENZOFURAN DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-07-09 EP claimed
US-4558143-A Process for preparing 4-oxo-4,5,6,7-tetrahydrobenzofuran SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-12-10 US claimed
EP-0101003-A1 Process for preparing 4-oxo-4,5,6,7-tetrahydrobenzofuran derivative SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-02-22 EP claimed
EP-0101004-A1 Process for preparing 4-oxo-4, 5, 6, 7-tetrahydroindole derivative SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-02-22 EP claimed