Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.32 |
| ▸ | ELOC | Q15369 | 1/20 | 0.32 |
| ▸ | ELOB | Q15370 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864191 | 0.89 | VHL (0.41) | ALDH1A1VHLELOCELOB | |
| SCHEMBL3129135 | 0.68 | HSD17B10 (0.39) | ALDH1A1MAOAMAOBCYP2A6PRKCI | |
| SCHEMBL333300 | 0.68 | MAPT (0.42) | ALDH1A1MAOAMAOBCYP2A6PRKCI | |
| SCHEMBL9865054 | 0.67 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1551445 | 0.65 | HPGD (0.56) | ALDH1A1MAOAMAOBCYP2A6VHL | |
| SCHEMBL10513879 | 0.64 | ALDH1A1 (0.43) | ALDH1A1MAOAMAOBCYP2A6 | |
| SCHEMBL14591138 | 0.63 | — | — | |
| SCHEMBL20165295 | 0.61 | MAOA (0.54) | ALDH1A1MAOAMAOBVHLELOC | |
| SCHEMBL5203764 | 0.61 | VHL (0.51) | ALDH1A1MAOAMAOBVHLELOC | |
| SCHEMBL17495034 | 0.61 | CASP1 (0.49) | ALDH1A1MAOAMAOBCYP2A6VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045561-A | Substituted furan sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1991-09-03 | — | — | US | disclosed |