Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339463 | 1.00 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3339457 | 1.00 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3339459 | 1.00 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3339471 | 1.00 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3333019 | 1.00 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL499685 | 0.91 | REN (0.49) | RENCYP3A4 | |
| SCHEMBL499136 | 0.91 | REN (0.49) | RENCYP3A4 | |
| SCHEMBL8082213 | 0.90 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL10253830 | 0.90 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL3335502 | 0.85 | REN (0.54) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144825-A1 | Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144825-A1 | Renin Inhibitors | ACE, REN, DNPEP | REN 2/4885CYP3A4 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.