Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499136 | 1.00 | REN (0.49) | RENCYP3A4 | |
| SCHEMBL3339471 | 0.91 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3339457 | 0.91 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3339463 | 0.91 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3333019 | 0.91 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3333015 | 0.91 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL3339459 | 0.91 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL10253830 | 0.87 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL8082213 | 0.87 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL498921 | 0.84 | REN (0.39) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106221-B2 | Renin inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |