SCHEMBL333313

SCHEMBL333313

Nc1ccc(Cl)cc1C(=O)c1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 1.00
GABRP O00591 1/20 0.58
GABRD O14764 1/20 0.58
GABRA1 P14867 1/20 0.58
GABRB1 P18505 1/20 0.58
GABRG2 P18507 1/20 0.58
GABRB3 P28472 1/20 0.58
GABRA5 P31644 1/20 0.58
GABRA3 P34903 1/20 0.58
GABRA2 P47869 1/20 0.58
GABRB2 P47870 1/20 0.58
GABRA4 P48169 1/20 0.58
GABRE P78334 1/20 0.58
GABRA6 Q16445 1/20 0.58
GABRG1 Q8N1C3 1/20 0.58
GABRG3 Q99928 1/20 0.58
GABRQ Q9UN88 1/20 0.58
RORB Q92753 3/20 0.55
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29516764 1.00 RECQL (1.00) RECQLGABRPGABRDGABRA1GABRB1
Hydrochloric Acid SCHEMBL8835389 0.98 RECQL (0.97) RECQLGABRPGABRDGABRA1GABRB1
Hydrazine SCHEMBL11776632 0.98 RECQL (0.97) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL3253860 0.89 RECQL (0.80) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL9540049 0.89 RECQL (0.79) RECQLALDH1A1KDM4ENPC1RAB9A
SCHEMBL2829388 0.88 RECQL (0.78) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL8296814 0.88 RECQL (0.78) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL11624724 0.87 RECQL (0.77) RECQLALDH1A1KDM4ENPC1RAB9A
SCHEMBL11842389 0.87 RECQL (0.77) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL29849818 0.86 RECQL (0.75) RECQLGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062390-A1 CONTINUOUS FLOW SYNTHESIS OF LORAZEPAM PURDUE RESEARCH FOUNDATION 2026-03-05 US claimed
WO-2024036115-A1 CONTINUOUS FLOW SYNTHESIS OF LORAZEPAM PURDUE RESEARCH FOUNDATION (US) 2024-02-15 WO claimed
CN-110606839-B Green synthesis method of polysubstituted quinazoline derivative 南方医科大学 2021-10-08 CN claimed
CN-112028844-A Preparation method of lorazepam intermediate 北京益民药业有限公司 2020-12-04 CN claimed
CN-111707752-A HPLC detection method of chlordiazepam related substances 山东新华制药股份有限公司 2020-09-25 CN claimed
EP-3470491-A1 PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS The Chemours Company FC, LLC (US) 2019-04-17 EP claimed
EP-2410032-B1 Phosphorus-containing stabilizers for fluoroolefins CHEMOURS CO FC LLC (US) 2018-11-14 EP claimed
US-20170362483-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS THE CHEMOURS COMPANY FC, LLC 2017-12-21 US claimed
EP-2420546-B1 Terephthalate stabilizers for fluoroolefins CHEMOURS CO FC LLC (US) 2017-04-26 EP claimed
EP-2057247-B1 ASCORBIC ACID STABILIZERS FOR FLUOROOLEFINS DU PONT (US) 2016-04-13 EP claimed
WO-2008027511-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2008027594-A2 PHENOL STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2008027515-A2 PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2008027512-A2 FUNCTIONALIZED PERFLUOROPOLYETHER STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2008027596-A2 BENZOPHENONE DERIVATIVE STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2008027519-A1 OXETANE STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2008027514-A1 TERPENE, TERPENOID, AND FULLERENE STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2008027513-A2 ARYL-ALKYL ETHER, POLYOXYALKYLATED AROMATIC, AND ALKYLATED AROMATIC STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
US-4511510-A PHTHALIMIDOGLYCINE, HYDRAZINE RAVIZZA S.P.A. (IT) 1985-04-16 US claimed
US-4010153-A Preparation of chiral 1,4-benzodiazepin-2-one-derivatives by reaction of (s)-α-amino acid chloride hydrochlorides etc. CRC COMPAGNIA DI RICERCA CHIMICA S.A. (CH) 1977-03-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062390-A1 CONTINUOUS FLOW SYNTHESIS OF LORAZEPAM GRIK4, GRIK5, POLM RECQL 449/4885GABRP 99/4885GABRD 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.