Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | FADS1 | O60427 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GCK | P35557 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253860 | 0.92 | RECQL (0.80) | RECQLFADS1NOS2SMN1; SMN2GFER | |
| SCHEMBL11624724 | 0.90 | RECQL (0.77) | RECQLFADS1NOS2SMN1; SMN2KMT2A | |
| SCHEMBL333313 | 0.89 | RECQL (1.00) | RECQLFADS1SMN1; SMN2GFERKMT2A | |
| SCHEMBL29516764 | 0.89 | RECQL (1.00) | RECQLFADS1SMN1; SMN2GFERKMT2A | |
| SCHEMBL6351799 | 0.88 | RECQL (0.64) | RECQLFADS1NOS2SMN1; SMN2GFER | |
| SCHEMBL28356361 | 0.87 | RECQL (0.73) | RECQLFADS1SMN1; SMN2GFERKMT2A | |
| Hydrochloric Acid SCHEMBL8835389 | 0.87 | RECQL (0.97) | RECQLFADS1SMN1; SMN2GFERKMT2A | |
| Hydrazine SCHEMBL11776632 | 0.87 | RECQL (0.97) | RECQLFADS1SMN1; SMN2GFERKMT2A | |
| SCHEMBL6954318 | 0.87 | RECQL (0.73) | RECQLFADS1NOS2SMN1; SMN2GFER | |
| SCHEMBL30484136 | 0.86 | RECQL (0.67) | RECQLSMN1; SMN2GFERKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070369-C | Alteration of hair growth | KASZYNSKI EDWIN G (US) | 2001-09-05 | — | — | CN | disclosed |
| CN-1071917-A | Quinazoline derivant as human immunodeficiency virus reversed transcriptive enzyme antagonist | MERCK & CO INC (US) | 1993-05-12 | — | — | CN | disclosed |
| EP-0530994-A1 | Quinazoline derivatives as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| WO-1993004047-A1 | QUINAZOLINE DERIVATIVES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1993-03-04 | — | — | WO | disclosed |
| CN-1047620-A | Alteration of hair growth | KASZYNSKI EDWIN G (US) | 1990-12-12 | — | — | CN | disclosed |
| CN-85101410-A | Alteration of hair growth | — | 1987-01-10 | — | — | CN | disclosed |