SCHEMBL3333365

SCHEMBL3333365

CCn1c2ccc(C(=O)c3ccc(-n4c5ccccc5c5ccccc54)cc3)cc2c2cc(C(=O)c3ccccc3C)ccc21

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.52
KDM4E B2RXH2 6/20 0.50
LMNA P02545 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PTGER4 P35408 3/20 0.48
MAPT P10636 5/20 0.48
HTT P42858 1/20 0.46
RORC P51449 3/20 0.45
POLB P06746 2/20 0.45
MAPK1 P28482 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
RECQL P46063 1/20 0.44
NPY5R Q15761 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3362382 0.92 KDM4E (0.46) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL3362377 0.92 KDM4E (0.46) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL30832750 0.91 KDM4E (0.57) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL29370263 0.91 KDM4E (0.57) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL3417160 0.91 KDM4E (0.57) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL24494726 0.87 ALDH1A1 (0.57) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL3130523 0.86 ALDH1A1 (0.57) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL3338376 0.84 ALDH1A1 (0.49) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL28516372 0.84 ALDH1A1 (0.53) CNR2KDM4ELMNAMEN1KMT2A
SCHEMBL30042372 0.83 LMNA (0.50) CNR2KDM4ELMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150056554-A1 Oxime Ester Photoinitiators CIBA CORPORATION (US) 2015-02-26 US disclosed
US-8911921-B2 Oxime ester photoinitiators CIBA CORPORATION (US) 2014-12-16 US disclosed
EP-2144876-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2012-09-12 EP disclosed
US-20100136491-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2010-06-03 US disclosed
EP-2144876-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2010-01-20 EP disclosed
WO-2008138724-A1 OXIME ESTER PHOTOINITIATORS BASF SE (CH) 2008-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100136491-A1 OXIME ESTER PHOTOINITIATORS CBR3, CCNE2, CBR1 CNR2 232/4885KDM4E 1003/4885LMNA 3594/4885
US-20150056554-A1 Oxime Ester Photoinitiators CBR3, CCNE2, CBR1 CNR2 232/4885KDM4E 1003/4885LMNA 3594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.