SCHEMBL3333369

SCHEMBL3333369

NC(=O)C(Cc1ccccc1)CC(N)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC1A1 P43005 3/20 0.81
▸ SLC1A3 P43003 1/20 0.81
▸ SLC1A2 P43004 1/20 0.81
▸ ALPI P09923 1/20 0.65
▸ PKM P14618 1/20 0.65
▸ PTGS1 P23219 1/20 0.65
▸ XIAP P98170 1/20 0.65
▸ SLC7A5 Q01650 1/20 0.65
▸ CYP1A2 P05177 1/20 0.58
▸ GRIK1 P39086 1/20 0.58
▸ GRM2 Q14416 1/20 0.56
▸ GRM3 Q14832 1/20 0.56
▸ ANPEP P15144 1/20 0.54
▸ RNPEP Q9H4A4 1/20 0.54
▸ DNPEP Q9ULA0 1/20 0.54
▸ CPA1 P15085 2/20 0.51
▸ CPA3 P15088 2/20 0.51
▸ FOLH1 Q04609 1/20 0.51
▸ CPB1 P15086 1/20 0.51
▸ CPB2 Q96IY4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1519045 1.00 SLC1A1 (0.81) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL31269773 0.92 SLC1A1 (0.69) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL2265548 0.89 SLC1A1 (1.00) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL8377822 0.89 SLC1A1 (1.00) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL130817 0.89 SLC1A1 (1.00) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL133913 0.89 SLC1A1 (1.00) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL8959957 0.88 SLC1A1 (0.96) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL16494899 0.86 SLC1A1 (0.81) SLC1A1SLC1A3SLC1A2ALPIPKM
SCHEMBL29386512 0.85 SLC1A1 (0.84) SLC1A1SLC1A3SLC1A2ALPIPKM
Ethylene Glycol SCHEMBL27596923 0.85 SLC1A1 (0.90) SLC1A1SLC1A3SLC1A2ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103596558-A polymer shell nanocapsules UNIV SANTIAGO COMPOSTELA 2014-02-19 — — CN disclosed
US-20100145018-A1 Lipid-Polymer-Conjugates ASTELLAS PHARMA EUROPE BV (NL) 2010-06-10 — — US disclosed
EP-1392755-B1 LIPID-POLYMER-CONJUGATES COMPOSITIONS ASTELLAS PHARMA EUROP B V (NL) 2008-12-03 — — EP disclosed
CN-1308375-C Lipid-polymer-conjugates compsns. YAMANOUCHI EUROP BV (NL) 2007-04-04 — — CN disclosed
EP-1392756-B1 LIPID-POLYMER-CONJUGATES ASTELLAS PHARMA EUROP B V (NL) 2007-02-14 — — EP disclosed
CN-1271116-C Lipid-polymer-conjugates YAMANOUCHI EUROP BV (NL) 2006-08-23 — — CN disclosed
CN-1602326-A Lipid-polymer-conjugates YAMANOUCHI EUROP BV (NL) 2005-03-30 — — CN disclosed
US-20040254352-A1 Lipid-polymer-conjugates YAMANOUCHI EUROPE B.V. (NL) 2004-12-16 — — US disclosed
US-20040241222-A1 Lipid-polymer-conjugates compositions ASTELLAS PHARMA EUROPE B.V. (NL) 2004-12-02 — — US disclosed
CN-1520435-A Lipid-polymer-conjugates compsns. ֮��ŷ�����޹�˾ 2004-08-11 — — CN disclosed
CN-1148227-C Therapeutical compound and its application 博立迈生物技术开发(深圳)有限公司 2004-05-05 — — CN disclosed
EP-1392756-A2 LIPID-POLYMER-CONJUGATES Yamanouchi Europe B.V. (NL) 2004-03-03 — — EP disclosed
EP-1392755-A1 LIPID-POLYMER-CONJUGATES COMPOSITIONS YAMANOUCHI EUROPE B.V. (NL) 2004-03-03 — — EP disclosed
WO-2002098951-A2 LIPID-POLYMER-CONJUGATES YAMANOUCHI EUROPE B.V. (NL) 2002-12-12 — — WO disclosed
WO-2002098952-A1 LIPID-POLYMER-CONJUGATES COMPOSITIONS YAMANOUCHI EUROPE B.V. (NL) 2002-12-12 — — WO disclosed
CN-1310025-A Therapeutical compound and its application AMERICAN FINNIE BIO SCIENCE IN (US) 2001-08-29 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145018-A1 Lipid-Polymer-Conjugates PARG, GLUL, PHOSPHO1 SLC1A1 77/4885SLC1A3 35/4885SLC1A2 93/4885
US-20040254352-A1 Lipid-polymer-conjugates PARG, GLUL, PARN SLC1A1 89/4885SLC1A3 41/4885SLC1A2 116/4885
US-20040241222-A1 Lipid-polymer-conjugates compositions PHOSPHO1, PARG, GLUL SLC1A1 63/4885SLC1A3 46/4885SLC1A2 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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