Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.81 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.81 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.57 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.57 |
| ▸ | CPA3 | P15088 | 3/20 | 0.56 |
| ▸ | CPA1 | P15085 | 2/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377822 | 0.89 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2CYP1A2ALPI | |
| SCHEMBL133913 | 0.89 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2CYP1A2ALPI | |
| SCHEMBL130817 | 0.89 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2CYP1A2ALPI | |
| SCHEMBL2265548 | 0.89 | SLC1A1 (1.00) | SLC1A1SLC1A3SLC1A2CYP1A2ALPI | |
| SCHEMBL8959957 | 0.88 | SLC1A1 (0.96) | SLC1A1SLC1A3SLC1A2CYP1A2ALPI | |
| SCHEMBL1519045 | 0.86 | SLC1A1 (0.81) | SLC1A1SLC1A3SLC1A2CYP1A2ALPI | |
| SCHEMBL3333369 | 0.86 | SLC1A1 (0.81) | SLC1A1SLC1A3SLC1A2CYP1A2ALPI | |
| SCHEMBL9622038 | 0.85 | CYP1A2 (0.86) | SLC1A1SLC1A3SLC1A2CYP1A2CPA3 | |
| SCHEMBL7439697 | 0.85 | CYP1A2 (0.86) | SLC1A1SLC1A3SLC1A2CYP1A2CPA3 | |
| SCHEMBL7432418 | 0.85 | CYP1A2 (0.86) | SLC1A1SLC1A3SLC1A2CYP1A2CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397488-B1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | FEDERAL STATE BUDGETARY INSTITUTION RES ZAKUSOV INSTITUTE OF PHARMACOLOGY (RU) | 2019-03-27 | — | — | EP | disclosed |
| US-9683014-B2 | Dipeptide mimetics of NGF and BDNF neurotrophins | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2017-06-20 | — | — | US | disclosed |
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII (RU) | 2015-04-23 | — | — | US | disclosed |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2011-12-22 | — | — | US | disclosed |
| EP-2397488-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | Uchrezhdenie Rossiiskoi Akademii Meditsynskikh Nauk Nauchno-issledovatelsky Institut Farmakologii Imeni V.V.Zakusova Ramn (RU) | 2011-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | SLC1A1 1230/4885SLC1A3 1723/4885SLC1A2 1010/4885 |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | SLC1A1 1230/4885SLC1A3 1723/4885SLC1A2 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.