Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888742 | 0.93 | CYP2D6 (0.36) | CYP2D6HPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2303349 | 0.86 | CYP2D6 (0.38) | CYP2D6HPGDALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3333528 | 0.77 | RECQL (0.34) | CYP2D6HPGDSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL15571072 | 0.76 | TAAR1 (0.39) | HPGDALDH1A1CYP3A4CYP2C9HTR2A | |
| SCHEMBL29077955 | 0.75 | CYP2D6 (0.37) | CYP2D6HPGDALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL29077956 | 0.75 | CYP2D6 (0.37) | CYP2D6HPGDALDH1A1CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL25431015 | 0.73 | CYP2D6 (0.36) | CYP2D6HPGDALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL6025678 | 0.73 | LIG1 (0.38) | SLC6A2SLC6A4SLC6A3RECQLHTR2A | |
| SCHEMBL6025232 | 0.73 | LIG1 (0.38) | SLC6A2SLC6A4SLC6A3RECQLHTR2A | |
| SCHEMBL6024476 | 0.73 | LIG1 (0.38) | SLC6A2SLC6A4SLC6A3RECQLHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | claimed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | BDKRB1, BDKRB2, BRS3 | CYP2D6 1247/4885HPGD 2320/4885SLC6A2 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.